Protein Info for IAI47_02450 in Pantoea sp. MT58

Annotation: septum formation inhibitor Maf

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00172: septum formation protein Maf
  • amino acids 3 to 181 (179 residues), 220.2 bits, E=8.1e-70
• PF02545: Maf
  • amino acids 4 to 184 (181 residues), 216.5 bits, E=1.3e-68

Best Hits

Swiss-Prot: 77% identical to NTPPA_SHISS: dTTP/UTP pyrophosphatase (yceF2) from Shigella sonnei (strain Ss046)

KEGG orthology group: K06287, septum formation protein (inferred from 97% identity to pva:Pvag_2821)

MetaCyc: 76% identical to nucleoside triphosphate pyrophosphatase YhdE (Escherichia coli K-12 substr. MG1655)
Nucleotide diphosphatase. [EC: 3.6.1.9]; 3.6.1.9 [EC: 3.6.1.9]

Predicted SEED Role

"Septum formation protein Maf" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

MetaCyc Pathways

• superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (18/18 steps found)
• superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) (14/14 steps found)
• pyrimidine deoxyribonucleotides de novo biosynthesis I (9/9 steps found)
• pyrimidine deoxyribonucleotides de novo biosynthesis II (7/7 steps found)
• pyrimidine deoxyribonucleotides de novo biosynthesis III (8/9 steps found)
• dZTP biosynthesis (3/5 steps found)
• pyrimidine deoxyribonucleotides dephosphorylation (1/3 steps found)
• tunicamycin biosynthesis (2/9 steps found)

KEGG Metabolic Maps

• Nicotinate and nicotinamide metabolism
• Pantothenate and CoA biosynthesis
• Purine metabolism
• Riboflavin metabolism
• Starch and sucrose metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.9

Protein Sequence (197 amino acids)

>IAI47_02450 septum formation inhibitor Maf (Pantoea sp. MT58)
MVTLYLASGSPRRRELLTQLGLTFERIVTDVEEQRQPNEAAEIYVRRLANDKAQAGVRLA
AQDLPVLGADTIVVLNGDVLEKPRDAAHAHAMLRKLSGHTHQVMTAVALADSQQALDCVV
TTDVTFRTLTETDIDDYIATGEPMDKAGAYGIQGRGGNFVRKINGSYHAVVGLPLVETAE
LISHFQSLRAVRGQHDG