Protein Info for IAI47_02040 in Pantoea sp. MT58

Annotation: peptidylprolyl isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00254: FKBP_C
  • amino acids 4 to 73 (70 residues), 34.2 bits, E=1.3e-12

Best Hits

Swiss-Prot: 85% identical to SLYD_SHIFL: FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (slyD) from Shigella flexneri

KEGG orthology group: K03775, FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC: 5.2.1.8] (inferred from 96% identity to pam:PANA_3638)

MetaCyc: 85% identical to FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (Escherichia coli K-12 substr. MG1655)
Peptidylprolyl isomerase. [EC: 5.2.1.8]; RXN-22956 [EC: 5.2.1.8]

Predicted SEED Role

"FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8)" in subsystem Peptidyl-prolyl cis-trans isomerase or Potassium homeostasis (EC 5.2.1.8)

MetaCyc Pathways

• NiFe(CO)(CN)₂ cofactor biosynthesis (1/10 steps found)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Protein Sequence (188 amino acids)

>IAI47_02040 peptidylprolyl isomerase (Pantoea sp. MT58)
MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISGLENALENHIAGDKFDV
HIPANDAYGQYDDNLVQRVPKDVFMGVDELQVGMRFLAETDQGPVPVEITEVEDEHVVVD
GNHMLAGQNLNFNVEVVAIREATPEELAHGHVHGADGHHHDHDHGHDHDHDHDHGKGGCG
TGGCGCSH