Protein Info for IAI47_01775 in Pantoea sp. MT58

Annotation: 4-alpha-glucanotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 693 PF21226: MalQ_N" amino acids 51 to 126 (76 residues), 29.1 bits, see alignment E=8.6e-11 TIGR00217: 4-alpha-glucanotransferase" amino acids 98 to 681 (584 residues), 766.1 bits, see alignment E=1.5e-234 PF02446: Glyco_hydro_77" amino acids 146 to 664 (519 residues), 448.7 bits, see alignment E=2.8e-138

Best Hits

Swiss-Prot: 60% identical to MALQ_ECOLI: 4-alpha-glucanotransferase (malQ) from Escherichia coli (strain K12)

KEGG orthology group: K00705, 4-alpha-glucanotransferase [EC: 2.4.1.25] (inferred from 93% identity to pva:Pvag_2961)

MetaCyc: 60% identical to 4-alpha-glucanotransferase (Escherichia coli K-12 substr. MG1655)
4-alpha-glucanotransferase. [EC: 2.4.1.25]; 2.4.1.25 [EC: 2.4.1.25]; 2.4.1.25 [EC: 2.4.1.25]; MALTODEG-RXN [EC: 2.4.1.25]; RXN0-7347 [EC: 2.4.1.25]

Predicted SEED Role

"4-alpha-glucanotransferase (amylomaltase) (EC 2.4.1.25)" in subsystem Glycogen metabolism or Maltose and Maltodextrin Utilization (EC 2.4.1.25)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.25

Use Curated BLAST to search for 2.4.1.25

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (693 amino acids)

>IAI47_01775 4-alpha-glucanotransferase (Pantoea sp. MT58)
MKQNALDQAARAAGISLDYINVNGEKAAISDETKRALLAVMDDPQDAKKSPLPPVAVFSG
SGKRQLTPQGSGVYSWQLQTEKGKQFSGELTAGEPFSLPGPLTQGYHQLTLTKGKKRWQT
RIIVAPRRCYLPPALEAGEKRWGALVQLYTVRSEQNWGIGDFGDLDQLLVQLAERGGDFV
GLNPLHALYPASAGFASPYSPSSRRWLNVIYIDVSQVADFQQSAAAQKWWKSAKTQKALT
KAREAEWVDYEAVMALKLTALRHAWAHFQARDNQSEEHQSWADFVREGGDSLRYQAAYDG
IQLERQADKTQQGGWPAWPEAWRNSQLPEVQQWCEQHEEEIAFWQWLQWLAQQQFSACWT
HSQALGMSVGLYRDLAVGVAEGSAETWHDPELYRLKASVGAPPDRLGPLGQNWGLPPMDP
HVMQARGYQPFIDMLRANMRDCGALRIDHVMSLLRLWWVPAGETADKGAYVAYPVNDLLG
ILALESHRLRCMVIGEDLGTVPQEIISLLRKSGVFSWKVLWFEQEKDQRYRAPQDYPRQS
IASASTHDLPTLTGFWEQGDLDLGEKLGLYPGDAVKALHQQRAAQKQALLDALHQAGALP
ARSQKKAEKLTMTPALNRAIHRFLADTESALLGLQPEDWLGMTTPVNVPGTVDQYPNWRR
KLSKTLEAIFADKEVNTLLKVVSEQRQSGQKGQ