Protein Info for IAI47_01420 in Pantoea sp. MT58

Annotation: sensor domain-containing diguanylate cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 322 PF13185: GAF_2" amino acids 27 to 154 (128 residues), 43.7 bits, see alignment E=5.1e-15 PF01590: GAF" amino acids 28 to 158 (131 residues), 69.1 bits, see alignment E=8.4e-23 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 163 to 319 (157 residues), 121.1 bits, see alignment E=2e-39 PF00990: GGDEF" amino acids 164 to 319 (156 residues), 120.6 bits, see alignment E=8.4e-39

Best Hits

KEGG orthology group: None (inferred from 92% identity to pva:Pvag_3038)

Predicted SEED Role

"FOG: GGDEF domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (322 amino acids)

>IAI47_01420 sensor domain-containing diguanylate cyclase (Pantoea sp. MT58)
MKAPEIAADEAQRLSQLRALNIMNTPAEERFDRLTRLARRLYDVPIALVSLLEEDHQWFK
SAQGYAPTGSPRNISFCGHAILQDEIMIVEDALQDERFHDNPLVTGEPHIRFYAGCPLRA
PGGAKMGTFCIIGREPRQFNEEDQATMRDLAAMAEAELIAFQTATCDELTQITNRRGFMT
LGQMVLNECQRKNRPACLTFLDLDKFKQINDTLGHREGDRALMDFANAMKVAFKHSDLFA
RLGGDEFVVLFDGLQQQQSEALLMQFDRYLHQQSVSLNRRYRLQFSSGVVEFDPANPQSL
EQLLHDSDKQMYLTKNQKRIAV