Protein Info for IAI47_01370 in Pantoea sp. MT58

Annotation: NAD(P)/FAD-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 394 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF07992: Pyr_redox_2" amino acids 4 to 163 (160 residues), 39.8 bits, see alignment E=2.1e-13 PF03486: HI0933_like" amino acids 4 to 392 (389 residues), 516.4 bits, see alignment E=2.6e-158 PF01266: DAO" amino acids 5 to 101 (97 residues), 31 bits, see alignment E=1.1e-10 PF01134: GIDA" amino acids 5 to 36 (32 residues), 19.4 bits, see alignment (E = 2.7e-07) PF12831: FAD_oxidored" amino acids 5 to 153 (149 residues), 33.6 bits, see alignment E=1.6e-11 PF00890: FAD_binding_2" amino acids 5 to 48 (44 residues), 34.6 bits, see alignment 7.1e-12 TIGR00275: flavoprotein, HI0933 family" amino acids 6 to 392 (387 residues), 426.6 bits, see alignment E=4.5e-132 PF13454: NAD_binding_9" amino acids 7 to 160 (154 residues), 22.6 bits, see alignment E=4.9e-08 PF13450: NAD_binding_8" amino acids 8 to 39 (32 residues), 26.8 bits, see alignment (E = 2.9e-09)

Best Hits

Swiss-Prot: 78% identical to YHIN_ECOLI: Uncharacterized protein YhiN (yhiN) from Escherichia coli (strain K12)

KEGG orthology group: K07007, (no description) (inferred from 97% identity to pva:Pvag_3049)

Predicted SEED Role

"NAD(FAD)-utilizing dehydrogenases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (394 amino acids)

>IAI47_01370 NAD(P)/FAD-dependent oxidoreductase (Pantoea sp. MT58)
MEQFDVIIIGAGAAGLFCAAQAGQRGLSVLLLDNGKKPGRKILMSGGGRCNFTNLYTEPA
AYLSHNPHFCKSALARYTQWDFIDMVNRHGIAWHEKTLGQLFCDDSAQQIVDLLLAECDK
GNVILRLRSEVLSVERDESGYTLQLNGSTVQAKKLVIASGGLSMPGLGATPFGYKIAEQF
GLNVYPTRAALVPFTLHKPLLEQLQTLSGVALDTTIDAQDGTRFKEAMLFTHRGLSGPAV
LQISSYWLPGEFVTIDLLPATPLEAFLTAQREAHPNLSLKNSLAKILPKRLVEVLQALKV
VPDITLKQLNSKQQTELAQTLHAWRIQPNGTEGYRTAEVTLGGVDTTQLSSKTMEARAVP
GLYFIGEVADVTGWLGGYNFQWAWSSAWACAQAL