Protein Info for IAI47_00495 in Pantoea sp. MT58

Annotation: uracil-xanthine permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 transmembrane" amino acids 34 to 58 (25 residues), see Phobius details amino acids 65 to 84 (20 residues), see Phobius details amino acids 123 to 142 (20 residues), see Phobius details amino acids 153 to 176 (24 residues), see Phobius details amino acids 189 to 207 (19 residues), see Phobius details amino acids 215 to 235 (21 residues), see Phobius details amino acids 255 to 275 (21 residues), see Phobius details amino acids 345 to 367 (23 residues), see Phobius details amino acids 374 to 394 (21 residues), see Phobius details amino acids 403 to 424 (22 residues), see Phobius details amino acids 433 to 453 (21 residues), see Phobius details TIGR00801: uracil-xanthine permease" amino acids 24 to 452 (429 residues), 462.5 bits, see alignment E=1.3e-142 PF00860: Xan_ur_permease" amino acids 29 to 421 (393 residues), 369.5 bits, see alignment E=8.8e-115 TIGR03173: xanthine permease" amino acids 36 to 454 (419 residues), 416.9 bits, see alignment E=8e-129

Best Hits

Swiss-Prot: 88% identical to XANP_SHIFL: Xanthine permease XanP (xanP) from Shigella flexneri

KEGG orthology group: K03458, nucleobase:cation symporter-2, NCS2 family (inferred from 98% identity to pva:Pvag_3216)

MetaCyc: 88% identical to xanthine:H+ symporter XanP (Escherichia coli K-12 substr. MG1655)
RXN-5076

Predicted SEED Role

"Xanthine permease" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (457 amino acids)

>IAI47_00495 uracil-xanthine permease (Pantoea sp. MT58)
MSTNPQPDQPSATQSELIYRLEDRPPLPQTLFAAGQHLLAMFVAVITPAILICQALGLPA
EDTRHVISMSLFASGVASLLQIKTWGPVGSGLLSIQGTSFNFVTPLIMGGMALKNGGADV
PTMMAALFGTLMVASCTEMVLSRVLHLARRIITPLVSGIVVMIIGLSLIQVGLTSIGGGF
SAMSDHTFGAPKNLMLAGAVLLVIVLLNRQKNPYLRVASLVIAMAVGYLLAWAMGMLPAA
GIPADQPLIVVPTPLYYGLGFDWNLLVPLMLVFMVTSLETIGDITATSDVSEQPVSGPLY
MKRLKGGVLANGLNSFVSALFNTFPNSCFGQNNGVIQLTGVASRYVGFVVALMLIVLGLF
PAVSGLVQMIPEPVLGGATIVMFGTIAASGVRIVSREPLNRRAIMIIALSLAVGLGVSQQ
PLILQFAPDWLKTLLSSGIAAGGITAIVLNLIFPPEK