Protein Info for IAI47_00440 in Pantoea sp. MT58

Annotation: Der GTPase-activating protein YihI

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 174 PF04220: YihI" amino acids 13 to 171 (159 residues), 189.6 bits, see alignment E=1.6e-60

Best Hits

Swiss-Prot: 71% identical to YIHI_ERWT9: Der GTPase-activating protein YihI (yihI) from Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)

KEGG orthology group: K09894, hypothetical protein (inferred from 92% identity to pva:Pvag_3227)

MetaCyc: 54% identical to Der GTPase-activating protein YihI (Escherichia coli K-12 substr. MG1655)
RXN-21992

Predicted SEED Role

"Protein of unknown function DUF414" in subsystem Experimental tye

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (174 amino acids)

>IAI47_00440 Der GTPase-activating protein YihI (Pantoea sp. MT58)
MKQPARAVHGKPAAKAKRKSRDDINNEARDRKRDKKHRGHASGSRANPAASDSNGGSQAN
NVKDPRIGSKKPVALIADGKTAAVKPKKSVEKPAAEKKARLTPEEELAKLENDERLDALL
DRLENGETLSAEDQGWLDASLDRIDELMEQLGIVMDDAEDEQAEEDMYRLLKGN