Protein Info for IAI47_00325 in Pantoea sp. MT58

Annotation: ATPase RavA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 498 transmembrane" amino acids 28 to 47 (20 residues), see Phobius details PF20030: bpMoxR" amino acids 10 to 211 (202 residues), 187.3 bits, see alignment E=5.5e-59 PF07728: AAA_5" amino acids 42 to 171 (130 residues), 92.7 bits, see alignment E=6.3e-30 PF17868: AAA_lid_8" amino acids 228 to 292 (65 residues), 73 bits, see alignment E=4.4e-24 PF20265: LARA_dom" amino acids 334 to 436 (103 residues), 131.2 bits, see alignment E=5.3e-42 PF12592: ATPase_RavA_C" amino acids 445 to 497 (53 residues), 72.1 bits, see alignment 9.1e-24

Best Hits

Swiss-Prot: 71% identical to RAVA_SALNS: ATPase RavA (ravA) from Salmonella newport (strain SL254)

KEGG orthology group: K03924, MoxR-like ATPase [EC: 3.6.3.-] (inferred from 98% identity to pva:Pvag_3249)

MetaCyc: 71% identical to regulatory ATPase RavA (Escherichia coli K-12 substr. MG1655)
Non-chaperonin molecular chaperone ATPase. [EC: 3.6.4.10, 5.6.1.7]

Predicted SEED Role

"Putative regulator protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.- or 3.6.4.10 or 5.6.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (498 amino acids)

>IAI47_00325 ATPase RavA (Pantoea sp. MT58)
MAQPHLLAERISRLSNALEKGLYERHHAIRLCLLAALSGESVFLLGPPGIAKSLIARRLK
YAFQHARAFEYLMTRFSTPEEVFGPLSIQALKDEGRYQRLTKGYLPDAEIVFLDEIWKAG
PAILNTLLTAINERRFRNGDSEETIPMRLLVTASNELPEADSGLEALYDRMLIRLWLDNV
HEKQNFRSMLTHQQDEHTNPVAESLRISDEEYAQWQLGISQVSLPDAVFELIYQLRQQLE
SQPAAPYISDRRWKKAIHLLQASAFYSGRNTIAPIDLILLKDCLWHDVASMQLLEREIDL
LMTQHAWQQQPMLMKLQQIKARRMALQQQQSIAQAITLEKHSGMFSRKPHYDLPESFTDE
QLTLMLQKPLMLHDMQVSHLVIARDALNQWLQKGGEVRGRLNGIGFAQSLDLHVDAQHCL
AIRDVSLQSSRLTLPGVSSSEPLPGEITDALDALESELRSQRHQFSQHQRCLFISDDWLA
RVETSLQDVAEQLKQARK