Protein Info for HSERO_RS22790 in Herbaspirillum seropedicae SmR1

Annotation: type I restriction-modification protein subunit M

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 860 transmembrane" amino acids 385 to 403 (19 residues), see Phobius details TIGR00497: type I restriction-modification system, M subunit" amino acids 4 to 483 (480 residues), 313.6 bits, see alignment E=1.2e-97 PF12161: HsdM_N" amino acids 6 to 150 (145 residues), 55.1 bits, see alignment E=1.4e-18 PF02384: N6_Mtase" amino acids 162 to 477 (316 residues), 323.6 bits, see alignment E=1.4e-100

Best Hits

KEGG orthology group: K03427, type I restriction enzyme M protein [EC: 2.1.1.72] (inferred from 100% identity to hse:Hsero_4561)

Predicted SEED Role

"Type I restriction-modification system, DNA-methyltransferase subunit M (EC 2.1.1.72)" in subsystem Restriction-Modification System (EC 2.1.1.72)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.72

Use Curated BLAST to search for 2.1.1.72

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IWZ0 at UniProt or InterPro

Protein Sequence (860 amino acids)

>HSERO_RS22790 type I restriction-modification protein subunit M (Herbaspirillum seropedicae SmR1)
VNKQQLAAKIWASANQMRSKIEANEYKDYILGFIFYKYLSDKLERFAVSQDFSKEDIQGL
SEDDEEIVNFFKSNLGYFISYPNLFSTWLALGGDFEVANVRVALSAFSRLIHPNHKRLFD
GIFKTLETGLSKLGESAASQTKAISALLQLIKDIPMDGRQGYDVLGFIYEYLISMFAANA
GKKAGEFYTPHEVSVLMSEIIAHHLKDRKTIQIYDSTSGSGSLLLNIGQAIAKHMVDKDN
IKYFAQELKENTYNLTRMNLVMRGILPSNIVTRNADTLEDDWPYFDDQDPVNSYNPLYLD
AVVSNPPYSQKWDPEHKEADPRYARFGLAPKSKADYAFLLHDLYHLKPDGIMAIVLPHGV
LFRGGEEGAIRKTLIENNHLETIIGLPSNIFFGTGIPTIILVLRQKRESSDVLIVDASKG
FAKEGKNNKLRACDIKKIADVVTGRLNVPGYSRLVPKAELQAKDYNLNIPRYVDSSEPAQ
SWDLYASMFGGIPQSELDALADFWTAFPALRTALFIDNGTPYVAPRVEALAKAIREHADV
IRYGGAFNTAFADFTPWLRGALLEKMLALQIPQQEALISEEIFARLTPLPLIDKYQAYQI
LDDHWQPIAVDLEIIQTEGFAATRVVDPHYVIKKKDGKEVEVQEGWRGRIMPFELVQMIH
HKRELDALREKENRLSEITASLEETLESFSEEDKANDTVNDAGDKFVPAAVAKEAKLLLA
EVKKSGDVEPESYEAKIIQVAEWFAEEKNLKAAIKKEAEALHLKTKKTIEGLTDAQVHIL
LERKWITPFIDELHGLPDQQIDTLVRKLEVLVEKYRITYADNAHEIQQVETTLAGMIEQL
DGSEFDLKGLAELKTLLAGN