Protein Info for HSERO_RS22780 in Herbaspirillum seropedicae SmR1

Annotation: DEAD/DEAH box helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1049 PF04313: HSDR_N" amino acids 20 to 210 (191 residues), 59.8 bits, see alignment E=7.4e-20 TIGR00348: type I site-specific deoxyribonuclease, HsdR family" amino acids 140 to 746 (607 residues), 329.9 bits, see alignment E=1.8e-102 PF04851: ResIII" amino acids 264 to 439 (176 residues), 102.8 bits, see alignment E=3.8e-33 PF18766: SWI2_SNF2" amino acids 268 to 479 (212 residues), 168.3 bits, see alignment E=4.2e-53 PF12008: EcoR124_C" amino acids 754 to 1034 (281 residues), 112.2 bits, see alignment E=6.7e-36

Best Hits

KEGG orthology group: K01153, type I restriction enzyme, R subunit [EC: 3.1.21.3] (inferred from 100% identity to hse:Hsero_4559)

Predicted SEED Role

"Type I restriction-modification system, restriction subunit R (EC 3.1.21.3)" in subsystem Restriction-Modification System (EC 3.1.21.3)

Isozymes

Compare fitness of predicted isozymes for: 3.1.21.3

Use Curated BLAST to search for 3.1.21.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IWY8 at UniProt or InterPro

Protein Sequence (1049 amino acids)

>HSERO_RS22780 DEAD/DEAH box helicase (Herbaspirillum seropedicae SmR1)
MTTFAKESDFEVALIDVLRQRGWGDADVIKNPTEADLLANWKQILFENNRAKDSLNEVPL
TDSEMQQIMEQITALRTPLKLNGFINGKTVSITRDNPADSLHLGKEVSLKIYDRLEIAAG
QSRYQIAQQPRYVRGSPLLNDRRGDLLLLINGMPVIHIELKKSSVPVSQAYNQIEKYSRE
NIFSGLFSLIQIFVAMEPAEALYFANPGPDSKFNKDYAFHWADYNNEPINDWKTFTASLL
SIPMAHQLIGFYTVADESDGVLKVMRSYQYYAAHAISDKVAKTDWKNPDRLGGHVWHTTG
SGKTMTSFKSAQLIANSKDADKVVFLLDRIELGTQTLQNYRNFAGDSNEVQATEYTEVLV
KKLKSADPADTLIVSSIQKMSRLKDEEDGLKGDDLEKMRAKRIVFIVDECHRSTFGDMLI
DIKESFPGAVFFGFSGTPIHKENIRKDNTTIDVFGGELHRYSIADGIRDKNVLGFDPYMV
MTYRDKDVRQAVALVKAKAASPTEAFADPKKKKVFNRYMNEVPMAGHRDSSGVYQSGIED
HLPISQYECDEHRHAVVQDIANNWVTLSQGHKFHAILATSSIPDAIIYYRLMKAQCPQLK
VTALFDPNINDDDGGCDPEFKTAGLVEIIGDYNATYGQTFDLGTHAGFKKDLAARLAHKR
PYQRIEAEPEKRLDLLIVVNQMLTGFDSKWVNTLYLDKLLAYENIIQAFSRTNRLFGPDK
PFGTIRYYRKPHTMKRNVAAAVKLYSGDKPIGLFADRLPINLERMNACFVEICAIFSAAG
ITDFSKLPDDLAARAAFAKQFNRFSAILEAARIQGFTWEKSVYEFGDDAKMQVTLTISHH
QYLTLLQRYKELGGGSVGSGESIPFDIDSHITEIDTGKIDADYMNSRFAKFLKVLHGGDE
QAKEATLAELHRSFTSLSQEDQRIAEIFLHDIQRGDVQIDPNRTFRDYLADYQAQAKNKE
IEAIVEGLGIDASKLLALMNAKTTDVNLNEFGRFDALLATVDKQKAKAYFEAQEGKSIPA
FKVNIKTENLLRMFIVHGDFALDVSNEKT