Protein Info for HSERO_RS22550 in Herbaspirillum seropedicae SmR1

Annotation: ligand-gated channel protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 817 signal peptide" amino acids 1 to 40 (40 residues), see Phobius details PF07715: Plug" amino acids 163 to 267 (105 residues), 86.9 bits, see alignment E=1.3e-28 TIGR01783: TonB-dependent siderophore receptor" amino acids 165 to 816 (652 residues), 316.6 bits, see alignment E=2e-98 PF00593: TonB_dep_Rec" amino acids 363 to 785 (423 residues), 183.9 bits, see alignment E=1.1e-57

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 100% identity to hse:Hsero_4512)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IWU1 at UniProt or InterPro

Protein Sequence (817 amino acids)

>HSERO_RS22550 ligand-gated channel protein (Herbaspirillum seropedicae SmR1)
MSLFRRTHMSPLSRPRALSPRWWPLAPALMVTAALHAQAVQQRFDIPPGPLEQVLARFAQ
AADVPLALQSGKLQGQHSPGLAGSYSVQAGFDALLAGSGYRIGKTASGYVLVPASEAATP
SAATTPAASGSLPAIQISASADPGEQRWTARDSASTTKTATPLIEVPQSISVVTAERIAA
MGATTARDALGYTPGVNISPYGSDSRYDWINLRGFDAYSPGFYLDGLPLRNANSFAVWRT
ENYGIEQLAVLRGPASVLYGQAGPGGVVNVVSKLPSADAPRELQVQLGSDRRRQVGADIG
GAIDADGRLLYRVIGVVRDAELPAGGMKNDRLYLAPSLVWKISAATSLTLQAALLRDQGG
VYTRTRPLVGSLVPTAIGTTIPSELYTGNPHFDHFSQDQELFGYRLAHRFDERFAFTQSA
RVGHMSTDYRAVQTPRFATLNAANPNDPVNFQNLTRNLFGSRESATMFSIDNQLQADFST
GAVRHTVLAGVDYQRSRFDAVSFSGGSAPLLNIAAPSYPNGPFVVPAPYSDNRAVLTQTG
IYLQDQIKWNNGWEVTLGGRHDSASSTVDNRLDGSRTSSTDRKFTRRAAVLYHAANGLAP
YLSYTESFNPTATVNPLTNQSFGPETGKQTEVGLRYQPPGTNDLYSAALFDLKRQNYISY
DANFMPTQKGEIAVRGLELEAVTQPMAALRLTAAYSYTPRAVVTASSRPAEIGKQAAAVL
LHQFSVWGDHRLGNGVRLGLGARYVSATSGNGGGTPVKVPGYTLLDGLLGYDFARWSLAL
NLRNLTDKRYLTNCDTTASMCYYGDQRSVLATASYRW