Protein Info for HSERO_RS22455 in Herbaspirillum seropedicae SmR1

Annotation: AraC family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 418 PF13377: Peripla_BP_3" amino acids 115 to 271 (157 residues), 102 bits, see alignment E=6e-33 PF12833: HTH_18" amino acids 310 to 389 (80 residues), 66.4 bits, see alignment E=3.5e-22 PF00165: HTH_AraC" amino acids 357 to 387 (31 residues), 30.7 bits, see alignment (E = 4e-11)

Best Hits

Swiss-Prot: 46% identical to XYLR_ECOLI: Xylose operon regulatory protein (xylR) from Escherichia coli (strain K12)

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 100% identity to hse:Hsero_4493)

Predicted SEED Role

"Xylose activator XylR (AraC family)" in subsystem Xylose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IWS2 at UniProt or InterPro

Protein Sequence (418 amino acids)

>HSERO_RS22455 AraC family transcriptional regulator (Herbaspirillum seropedicae SmR1)
VAKAPTVHRIALLFNGNKIFDREIIAGIGEYISSTRASWDLYLEEDFRCRPQGIERWAGH
GIIADFDDPVTTAALEGVQLPVVAIGGSYADPSQYPANRPYVATDNYKMVKLAYDHLIEA
GLQHFALFSLPESDCNRWAQERERIFTDLTGADGIAGHIYRGVGTSAQSWDTAVEQQIAW
VRSLPKPVGIIAVTDARARQLLQACLFAGIAVPEQVALIGIDNDPLARVLTRIPLSSVIQ
GSVEMGRTAAHLLHQMLHGARFPDTRIMVPPVGINVLASSRHEVRNHPHVMQALHFIRQY
ACQGIKTDQVADYVGISRSSLEWYFRRELGRSVHDEILRFKLDAAKRLLEQAGSHAAEIA
VSCGFTSVQYMHAVFKRELGCTPREYQEQFAAGLERAAAPAARQKKKSAGTTLLEPTR