Protein Info for HSERO_RS21970 in Herbaspirillum seropedicae SmR1

Annotation: potassium transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 606 transmembrane" amino acids 6 to 22 (17 residues), see Phobius details amino acids 29 to 48 (20 residues), see Phobius details amino acids 54 to 73 (20 residues), see Phobius details amino acids 85 to 107 (23 residues), see Phobius details amino acids 113 to 134 (22 residues), see Phobius details amino acids 146 to 168 (23 residues), see Phobius details amino acids 180 to 201 (22 residues), see Phobius details amino acids 216 to 233 (18 residues), see Phobius details amino acids 239 to 256 (18 residues), see Phobius details amino acids 268 to 288 (21 residues), see Phobius details amino acids 294 to 312 (19 residues), see Phobius details amino acids 324 to 345 (22 residues), see Phobius details amino acids 357 to 376 (20 residues), see Phobius details TIGR00932: transporter, monovalent cation:proton antiporter-2 (CPA2) family" amino acids 12 to 283 (272 residues), 270.2 bits, see alignment E=1.1e-84 PF00999: Na_H_Exchanger" amino acids 13 to 372 (360 residues), 210.9 bits, see alignment E=2.8e-66 PF02254: TrkA_N" amino acids 402 to 508 (107 residues), 82.2 bits, see alignment E=3.8e-27

Best Hits

KEGG orthology group: K11745, glutathione-regulated potassium-efflux system ancillary protein KefC (inferred from 100% identity to hse:Hsero_4394)

Predicted SEED Role

"Glutathione-regulated potassium-efflux system protein KefC" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IVQ3 at UniProt or InterPro

Protein Sequence (606 amino acids)

>HSERO_RS21970 potassium transporter (Herbaspirillum seropedicae SmR1)
MDEQLLIALVYLLAAVAAVPIAKRLGLGAVLGYLLAGIVIGPWGLGLITEVKHILEFSEF
GVVLLLFLIGLELDPKRLWALRRSIFGWGSIQVAAVSLALLAAALAASVPWRIGLIGALG
MSLSSTAIALATLGERKLTATPAGSAAFSILLFQDIAAIPMMAAVPLLGVAASQGSGQGW
LHAGQVALVIALLIFGGRVLMRPILRIIAKTDMREIFTAFALLLVIATCLLMQSVGMSMA
LGTFLAGVLLADSEYRHALESDLEPFKGLLLGLFFIAVGMSVDFGVFFAQPWRILGMVLG
FLAIKTCVMWALGRCFGIPRGQQLFFAFLLSQGGEFAFIVFGAAVTAKVLTPETSSLLVV
VVALSMLVTPLLLLVHDRLLVRWMEGGKRRPEDKIDPQDHAVIIAGFGRFGQIIGRLLAA
NGIGATVLDHDPDQIDFLRKFGFKVFYGDATRIDLLRTAGADKARVLVIAIDDAQAALEM
VDKVREEFPHLQIAARARNVTHYYDLMDRGVTVLERETFESALHMGRQVLQQLDFGAYRA
REAAMKFRAHNLKTLEALYPHYKNQAQMVSMAVQAREELEAMFAGDRQAMEREHSHDQWR
GEPPPQ