Protein Info for HSERO_RS21675 in Herbaspirillum seropedicae SmR1

Annotation: insertase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 565 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 368 to 389 (22 residues), see Phobius details amino acids 433 to 458 (26 residues), see Phobius details amino acids 481 to 502 (22 residues), see Phobius details amino acids 521 to 542 (22 residues), see Phobius details TIGR03593: membrane protein insertase, YidC/Oxa1 family, N-terminal domain" amino acids 4 to 366 (363 residues), 366.8 bits, see alignment E=1.7e-113 PF14849: YidC_periplas" amino acids 86 to 357 (272 residues), 293.3 bits, see alignment E=2.9e-91 TIGR03592: membrane protein insertase, YidC/Oxa1 family" amino acids 367 to 557 (191 residues), 239 bits, see alignment E=4.5e-75 PF02096: 60KD_IMP" amino acids 368 to 557 (190 residues), 222 bits, see alignment E=4.4e-70

Best Hits

Swiss-Prot: 64% identical to YIDC_JANMA: Membrane protein insertase YidC (yidC) from Janthinobacterium sp. (strain Marseille)

KEGG orthology group: K03217, preprotein translocase subunit YidC (inferred from 100% identity to hse:Hsero_4336)

Predicted SEED Role

"Inner membrane protein translocase component YidC, long form"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IUS2 at UniProt or InterPro

Protein Sequence (565 amino acids)

>HSERO_RS21675 insertase (Herbaspirillum seropedicae SmR1)
MDIKRTVLWVVFSFSLLLLWDGWMRHNGHQSMFFPSANPTQEQAAANPAAPTASPTGSPV
PQAGTPAPGAVPGADVAATATKGETIVITTDLVKASIDTVGGELKRLELLKQPDVVDPTK
NVVLFDSEPGHMYLAESGLIGGPFPNHKTIFTAQAGPRTLDNGNEIQLVLVADQGGVKLT
KTYTFKRDSYLIDVKHTVTNTTGAAINPSLYLQLVRDGNKPGGESHFYSTFTGPAVYSNS
EHFEKLDFEKIANGKQQHVNKTDNGWIAMVQHYFVSAFIPPQNAQRDVFSKKVGDNLYAV
GSILPLGTVAPNASVTMDSQLYSGPTVSKTLQAIAPGLDLVRDYGHLTVIAEPIFWLMTH
IHNIVGNWGWTIILLTVLIKLIFFPLSAASYRSMAKMKAVSPKMQAIRERHKGDPQAMNR
EMMTLYKTEKINPLGGCLPIAIQIPVFIALYSVLLASVEMRGAPWLGWVHDLTAPDRLFG
TIPYFNMPIGLLPIIMAASMFLQTKLNPTPPDPVQAKVMMFMPLVFSFMFFFFPSGLVLY
WVTNNILSIAQQWVITRNIESGKTK