Protein Info for HSERO_RS19540 in Herbaspirillum seropedicae SmR1

Annotation: adenine glycosylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 378 TIGR01084: A/G-specific adenine glycosylase" amino acids 25 to 285 (261 residues), 348.1 bits, see alignment E=2e-108 PF00730: HhH-GPD" amino acids 55 to 184 (130 residues), 80.2 bits, see alignment E=2.1e-26 PF00633: HHH" amino acids 119 to 147 (29 residues), 28.4 bits, see alignment (E = 1.6e-10) PF14815: NUDIX_4" amino acids 253 to 365 (113 residues), 76.6 bits, see alignment E=2e-25

Best Hits

KEGG orthology group: K03575, A/G-specific adenine glycosylase [EC: 3.2.2.-] (inferred from 100% identity to hse:Hsero_3914)

Predicted SEED Role

"A/G-specific adenine glycosylase (EC 3.2.2.-)" in subsystem DNA repair, bacterial (EC 3.2.2.-)

Isozymes

Compare fitness of predicted isozymes for: 3.2.2.-

Use Curated BLAST to search for 3.2.2.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IS44 at UniProt or InterPro

Protein Sequence (378 amino acids)

>HSERO_RS19540 adenine glycosylase (Herbaspirillum seropedicae SmR1)
MKGVVESRRKAPASAEAGQYEDPSFSAAVIAWQKQHGRHKLPWQNTRDAYRVWLSEIMLQ
QTQVAAVIPYYQRFLERCPDVFALAAAPSEDVMALWSGLGYYTRARNLHKCAQRVVEQYG
GRFPDDPDLLADLPGIGRSTAAAIAAFSYGRRAAILDGNVKRVFARVFGIDGYPGAKPIE
DKLWLRAVALLPDQDIESYTQGLMDLGATLCVRGKPACERCPLAGRCVALAQDRVAELPV
SKPKKAVPERETVMLVITHGEDVLLEQRPDSGIWGGLLSLPEIAVGGAAQFDTAVRTLVA
PYGELQGCRKLQPFSHVFTHFKLHVAPFQVAMQSRSQRIAEGALVWYPVARLGEAPLPAP
VKKLLLGALRSDDLLATV