Protein Info for HSERO_RS18635 in Herbaspirillum seropedicae SmR1

Annotation: signal transduction protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 544 transmembrane" amino acids 7 to 29 (23 residues), see Phobius details amino acids 243 to 261 (19 residues), see Phobius details PF12792: CSS-motif" amino acids 39 to 224 (186 residues), 77.7 bits, see alignment E=8.7e-26 PF00563: EAL" amino acids 272 to 504 (233 residues), 217.3 bits, see alignment E=2.1e-68

Best Hits

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_3732)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IR84 at UniProt or InterPro

Protein Sequence (544 amino acids)

>HSERO_RS18635 signal transduction protein (Herbaspirillum seropedicae SmR1)
VSNKNRIVAWTIVATAVAAIAPVAAMMWLSRQAVAQAEHERLARYAESVIARAAHSFDET
QRSLKSLSPLLLLPCSDEHIAQMRLISVNSRSIEEMGYYEHGQLKCTSWDSSVGARRRRQ
AEPVFTTADGVEVALDQRSFVADGPTMLSIQYGAHSALVHRLRFVDVVLEKGVHVVLARN
GFGPVAQYGGPVAAGVAEHALDGLGRQDVDGFFISTVSRDGWTAAAIVDGDHVLEEMTGQ
QRWFLPVGILLGIGLVMLVLRVSQARLSPLADLQLAVKKKEFIVHYQPIIEMASGRCIGA
EALLRWRRPDGSIVRPDFFIALAEESGLILPLTDLVVDTVVREMRDTLRQDRALHIAINV
AAQDMKTGRILEVVSQALAGSDIRPEQLWMEATERGCMDIASASLTLARAREMGHSMALD
DFGTGYSNLQYLQGLPMDALKIDKSFVSTIGTGAATSAVIDHIIAMAKSLKLYIVAEGVE
TLEQAAYLAERGVDFAQGWLFSRPLPVEEFVAFYCATLADYGSGPEIIRGPQPASTDSPA
ALDA