Protein Info for HSERO_RS18375 in Herbaspirillum seropedicae SmR1

Annotation: diguanylate cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 324 PF13185: GAF_2" amino acids 26 to 155 (130 residues), 36.9 bits, see alignment E=6.5e-13 PF01590: GAF" amino acids 27 to 159 (133 residues), 64.3 bits, see alignment E=2.6e-21 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 163 to 321 (159 residues), 129.7 bits, see alignment E=4.6e-42 PF00990: GGDEF" amino acids 165 to 321 (157 residues), 126.5 bits, see alignment E=1.3e-40

Best Hits

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_3682)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IR34 at UniProt or InterPro

Protein Sequence (324 amino acids)

>HSERO_RS18375 diguanylate cyclase (Herbaspirillum seropedicae SmR1)
MRIAELPANEAARIDALHSLRILDTPREERFDRLTRLARRLFDVPMAVVTMIDVNRQWFK
SCVGLGDATETSREVSFCAHAILHEEMTIVPDATLDPRFSGNPQVTGEPFIRFYAGCPIK
SESGFTLGTLCLVDTVPRSFDADERALLKDLAAMVEQELTAVRMATIDELTGISNRRGFD
ALARHALANSRRMDWPACMLYFDLDQFKQINDRFGHAEGDAALVDFAALLSSSFRESDVI
ARLGGDEFAVFLTNADLAESDTVLAHFAQSVREFNVLRPRPYALAYSVGVVQYDAARHAD
LAALQHSADALMYERKKTRRAQAG