Protein Info for HSERO_RS17980 in Herbaspirillum seropedicae SmR1

Annotation: GTP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 613 PF00009: GTP_EFTU" amino acids 7 to 198 (192 residues), 189.6 bits, see alignment E=1.1e-59 TIGR01394: GTP-binding protein TypA/BipA" amino acids 8 to 606 (599 residues), 952 bits, see alignment E=1.1e-290 TIGR00231: small GTP-binding protein domain" amino acids 8 to 137 (130 residues), 81.4 bits, see alignment E=6.3e-27 PF01926: MMR_HSR1" amino acids 11 to 132 (122 residues), 26 bits, see alignment E=2.2e-09 PF03144: GTP_EFTU_D2" amino acids 222 to 293 (72 residues), 44.2 bits, see alignment E=5.4e-15 PF00679: EFG_C" amino acids 402 to 483 (82 residues), 86.9 bits, see alignment E=1.9e-28 PF21018: BipA_C" amino acids 492 to 600 (109 residues), 160.8 bits, see alignment E=2.2e-51

Best Hits

Swiss-Prot: 63% identical to TYPA_ECO27: GTP-binding protein TypA/BipA (typA) from Escherichia coli O127:H6 (strain E2348/69 / EPEC)

KEGG orthology group: K06207, GTP-binding protein (inferred from 100% identity to hse:Hsero_3601)

Predicted SEED Role

"GTP-binding protein TypA/BipA" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IQG7 at UniProt or InterPro

Protein Sequence (613 amino acids)

>HSERO_RS17980 GTP-binding protein (Herbaspirillum seropedicae SmR1)
MSNNIRAIRNIAIIAHVDHGKTTLVDQLLRQSGTFRDNQQVDNRVMDSNDIEKERGITIL
SKNCAVEYKGTHINIVDTPGHADFGGEVERVLSMVDSVLLLVDAQEGPMPQTRFVTRKAL
ALGLKPIVVLNKIDRPGARAEWAINATFELFDKLGATEEQLDFPVIYASGLNGYASLDPE
AREGNMEPLFDAILKYVPARKDDPDAPLQLQITSLEYSSYVGKIGVGRILAGRVKGGQDV
VWMNGPDDKPTKARINQVLTFKGLERVLVDEALAGDIVLINGIEEIGIGSTICSPDAPNG
LPMLKVDEPTLTMNFMVNTSPLAGREGKFVTTRQIRDRLEKELKSNMALRVVQAENDDST
YEVSGRGELHLTILIENMRREGFELAVSRPRVVFRMVNGVREEPYENLTVDVEETHQGGV
MEELGRRRGDLQNMEPDGKGRVRLEYHIPARGLIGFQGEFMTLTRGTGLMSHVFDDYKPV
DTTKGELAGRRNGVLISQDDGAAVAYALWKLQDRGRMFVSHNDPVYEGMIIGIHSRDNDL
VVNPIKGKQLTNVRASGTDEAVRLVPPIELSLEYAVEFIEDDELVEVTPKSIRLRKRHLK
EHERKKASREESI