Protein Info for HSERO_RS17315 in Herbaspirillum seropedicae SmR1

Annotation: ATP-dependent helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1355 TIGR01967: RNA helicase HrpA" amino acids 50 to 1030 (981 residues), 1410.9 bits, see alignment E=0 PF00270: DEAD" amino acids 71 to 218 (148 residues), 29.2 bits, see alignment E=2.3e-10 PF00271: Helicase_C" amino acids 304 to 420 (117 residues), 44.3 bits, see alignment E=5.7e-15 PF04408: HA2_N" amino acids 484 to 513 (30 residues), 24.2 bits, see alignment (E = 8.6e-09) PF21010: HA2_C" amino acids 514 to 569 (56 residues), 34 bits, see alignment (E = 1e-11) PF07717: OB_NTP_bind" amino acids 638 to 714 (77 residues), 46.3 bits, see alignment 1.2e-15 PF11898: DUF3418" amino acids 729 to 1351 (623 residues), 732.4 bits, see alignment E=1.3e-223

Best Hits

Predicted SEED Role

"macromolecule metabolism; macromolecule synthesis, modification; dna - replication, repair, restr./modif."

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IPP1 at UniProt or InterPro

Protein Sequence (1355 amino acids)

>HSERO_RS17315 ATP-dependent helicase (Herbaspirillum seropedicae SmR1)
MSVTKAPTPAPAAQPQKNPQQERARGQRDARGPRRTDSAAEAAPAPAPLRNPLPPVTFPE
ELPVSGRRHEIAAALRAHQVIIVSGETGSGKTTQLPKICLELGRGEKGLIGHTQPRRIAA
SSTAKRIAQELNSPPGELVGYKVRFNDTLSKGAWIKLMTDGILLAETQTDPLLRQYDTII
IDEAHERSLNIDFLLGYLKQLLPKRPDLKIIITSATIDADRFARHFGREVKGEIVPAPVI
EVSGRLYPVEIRYRPIDNADRSGVSTEVAQARARAEGRASQAQKDREQRDLMDAVVDAVD
ELARIGAGDVLVFLPGEREIRDAAEALRKHHPPHVEILPLFARLSAQEQERVFKTSNARR
IVLATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIEPVAQSAANQRAGRCGRV
AAGVCIRLYDEQDFLQRPKFTDPEILRSSLASVILRMKSLHLTDVESFPFIEPPLGRAIA
DGYQLLQELGAVEEQGGVNRLTPLGKQLARLPLDPRVGRMILAGRDNACLTELLIIAAAV
SVQDPRDRPMDAQNAADNAHKKFADEKSEFASYLKIWKWFEDAIAHKKSNRQLQEHCREN
FLSQLRLREWRDVHSQLLTIVKEQGWRLNEAPATYDQLHLALLTGLLGNVGFKSEDDAQY
LGARGIKFNIWPGAHLTKKPGRWVMAAELVDTARLYARCVANIQPEWLEKLGGHLLKKSW
GEPRWEKRAAQVTASERATLYGLVVYSQRRINYGKINPAEAREIFIRDALVGGDFETRAP
FFAHNQKLVREIENLEHKSRRLDVLVDDELIIGFYDKLIPHDICNGVDFEKWHKEATAAD
PKLLYLNRDDLMRHEAAGVTTELFPKTMNVAGIAMALSYHFEPGAARDGVTLTVPLYALN
QVSADRCEWLVPGMLKEKVHLLLKSLPQKLRRHCVPLPDYAARFCERMEERKAFGRGNLI
DAIIADIREQITLLVKPSDFKQETLSAHHAMNFKIVDEHGRQLEMGRNLAALQAEFGGQA
RQQFQKLAEQVAIAPREDEDNAAPSPAAATSKGGTSAAPAAAAPASVGEYSNLTSWSFGE
LPELLEITRGSGKQAQTLIGFPALVDRKTHCDLEVFDDPAEAARFHYAGLRRLFALQMKE
QLKYLEKNIPGLQQMGMQFMALGSQEELREQILNAGLERAFLQDPLPRNADEFNRRRDEG
KARLGLLVNEIARLCGQILAEYHALPKKLQGIKAHAQAAADMQAQLSQLVGKRFVAETDY
GNLSHYPRYLKAINVRLDKLRADPARDTRLLAEWNSVALPYQRALKDRAGRADPKMTEFR
WMLEELRVSLYAQELKTPMPVSVKRLQKVWESMQR