Protein Info for HSERO_RS16370 in Herbaspirillum seropedicae SmR1

Annotation: peptidyl-prolyl cis-trans isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 180 PF00254: FKBP_C" amino acids 3 to 80 (78 residues), 21.9 bits, see alignment E=9.4e-09

Best Hits

Swiss-Prot: 41% identical to SLYD_YERPE: FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (slyD) from Yersinia pestis

KEGG orthology group: K03775, FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC: 5.2.1.8] (inferred from 100% identity to hse:Hsero_3272)

Predicted SEED Role

"FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8)" in subsystem Peptidyl-prolyl cis-trans isomerase or Potassium homeostasis (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8J1X0 at UniProt or InterPro

Protein Sequence (180 amino acids)

>HSERO_RS16370 peptidyl-prolyl cis-trans isomerase (Herbaspirillum seropedicae SmR1)
MKIAKNTVVSVNYKLSDAQNNLIEQSSEPMVYLHGGYHNTLPKIEEALDGKEAGYSTTIQ
VEPEDAFGEYDSELVKIEPVERLPQPLEVGMQFEGSPDDDSEESVIFTVTEVADGKAVLD
GNHPLAGIALRFELAVTEVRAASEEEVSHGHVHGPHGHHHHHHDEDEGEAGDHFRSQPLN