Protein Info for HSERO_RS14055 in Herbaspirillum seropedicae SmR1

Annotation: acyl-CoA dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 388 PF02771: Acyl-CoA_dh_N" amino acids 8 to 117 (110 residues), 92.8 bits, see alignment E=3.9e-30 PF02770: Acyl-CoA_dh_M" amino acids 122 to 220 (99 residues), 73.9 bits, see alignment E=1.8e-24 PF00441: Acyl-CoA_dh_1" amino acids 233 to 365 (133 residues), 118.1 bits, see alignment E=8.2e-38 PF08028: Acyl-CoA_dh_2" amino acids 249 to 362 (114 residues), 50.2 bits, see alignment E=6.3e-17

Best Hits

KEGG orthology group: K00249, acyl-CoA dehydrogenase [EC: 1.3.99.3] (inferred from 100% identity to hse:Hsero_2798)

Predicted SEED Role

"Probable acyl-CoA dehydrogenase (EC 1.3.99.3)" in subsystem Isoleucine degradation or Valine degradation (EC 1.3.99.3)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.3.99.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IYV8 at UniProt or InterPro

Protein Sequence (388 amino acids)

>HSERO_RS14055 acyl-CoA dehydrogenase (Herbaspirillum seropedicae SmR1)
MSYPTASDSHADLRDAVRDLCKTFPPEYWRKIDEARGYPEQFVDALTKAGWLAALIPQEY
GGSGLGLTEASVIMEEINRTGGNSGACHGQMYNMGTLLRHGSPEQKERYLPRIASGELRL
QSMAVTEPTTGTDTTRIKTVAVKKGDRYVINGQKVWISRVQHSDLMILLARTTPLEQVSR
KSEGMSIFLVDLKEAIGHGMEVRPILNMVNHETNELFFDNLEIPAENLIGEEGRGFRYIL
DGLNAERTLIAAECIGDGYWFIDKATQYARERVVFDRPIGMNQGVQFPLAEAYIEVEAAN
LMRYQACALFDAQQSCGAQANMAKYLAAKAAWEAANVCLQTHGGFGFACEYDVERKFRET
RLYQVAPISTNLIFSYVAEHVLGLPRSF