Protein Info for HSERO_RS12250 in Herbaspirillum seropedicae SmR1

Annotation: adenosylmethionine--8-amino-7-oxononanoate aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 448 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details TIGR00508: adenosylmethionine-8-amino-7-oxononanoate transaminase" amino acids 17 to 436 (420 residues), 509.5 bits, see alignment E=2.9e-157 PF00202: Aminotran_3" amino acids 27 to 440 (414 residues), 313.7 bits, see alignment E=8.3e-98

Best Hits

KEGG orthology group: K00833, adenosylmethionine-8-amino-7-oxononanoate aminotransferase [EC: 2.6.1.62] (inferred from 100% identity to hse:Hsero_2450)

Predicted SEED Role

"Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)" in subsystem Biotin biosynthesis (EC 2.6.1.62)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.62

Use Curated BLAST to search for 2.6.1.62

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IWC9 at UniProt or InterPro

Protein Sequence (448 amino acids)

>HSERO_RS12250 adenosylmethionine--8-amino-7-oxononanoate aminotransferase (Herbaspirillum seropedicae SmR1)
MSGSASSALVARSLRSVWHPCTQMRRHESAPPIAITRAHGLWLHDSDGRRYLDAISSWWV
NLFGHTNTRINAALVEQLGQLEHAMLAGFTHEPVVALSEQLAALTGQALGHCFYASDGAS
AVEIALKMSVHAWRNGGQPDKNEFICIAGGYHGETVGALGVTDTPLFRSAYESLLRPAHV
AASPDARQAAPGESAEEVAARALDDVERILQQRQGRIAALIVEPLVQCAAGMAMHDPGYV
RGLRSLCDRYGAHLIADEIAVGCGRTGSFFACEQAGVWPDLLCLSKGISGGYLPLSLVMS
SEAIYQAFYDDDVRRGFLHSHSYTGNPLACRAALATLAIFAEDAVLERNRAFAPVLAAAL
QPLAQDPRVRHVRQRGMIWAYDAVLEGSAAATTAFSRRMAAEAAQREVLVRPIGASLYLM
PPYLLDEEQAHWLGRQLHAAFAATMEAL