Protein Info for HSERO_RS11455 in Herbaspirillum seropedicae SmR1

Annotation: N-formimino-L-glutamate deiminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 458 TIGR02022: formiminoglutamate deiminase" amino acids 2 to 456 (455 residues), 592.1 bits, see alignment E=3.6e-182 PF01979: Amidohydro_1" amino acids 45 to 431 (387 residues), 92.3 bits, see alignment E=1.9e-30

Best Hits

KEGG orthology group: K05603, formimidoylglutamate deiminase [EC: 3.5.3.13] (inferred from 100% identity to hse:Hsero_2289)

MetaCyc: 50% identical to formiminoglutamate deiminase subunit (Pseudomonas fluorescens)
Formimidoylglutamate deiminase. [EC: 3.5.3.13]

Predicted SEED Role

"Formiminoglutamic iminohydrolase (EC 3.5.3.13)" in subsystem Histidine Degradation (EC 3.5.3.13)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IUC6 at UniProt or InterPro

Protein Sequence (458 amino acids)

>HSERO_RS11455 N-formimino-L-glutamate deiminase (Herbaspirillum seropedicae SmR1)
LFCPLALLPQGWRSDVLLRWDGAGRLTHVTPDSARGSAALASGPVLPGMPNLHSHAFQRA
MAGLAETMGSPADSFWSWRELMYRFAQRLQPRQLEAIARQTYIEMLKAGYTSVCEFHYLH
HAPDGAPYADPAEMAWPLLQAAGQSGIGMTLLPVLYQQGGLGGRPVSAEQRRFVAAPSWL
LGLRERLLQHMPENDMRRYGVAPHSLRAVAPTGLEELLSGLAGQPGGSDAPIHIHVAEQL
REVEDCLAWSGQRPVQWLLSSQPVDARWCLVHATHMDDEEYRAVAGSGAVVGLCPTTEAN
LGDGVIDAPRLIDSAARWGIGSDSNIAISLRAELRLLEYAQRLHHRRRNVLAVIDAPAVA
DRLFCQALAGGAQAAGRAVAGLMPGQRADLVVLDPDHVNLAQRSSTQLLSALVFCEHDGP
MIGDVYVGGRQVVKEGRHALDDRAREDYRHALAALLKD