Protein Info for HSERO_RS10805 in Herbaspirillum seropedicae SmR1

Annotation: succinyldiaminopimelate aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 403 TIGR03538: succinyldiaminopimelate transaminase" amino acids 1 to 395 (395 residues), 607.5 bits, see alignment E=5.2e-187 PF00155: Aminotran_1_2" amino acids 32 to 392 (361 residues), 159.8 bits, see alignment E=5.7e-51

Best Hits

KEGG orthology group: K14267, N-succinyldiaminopimelate aminotransferase [EC: 2.6.1.17] (inferred from 100% identity to hse:Hsero_2163)

MetaCyc: 63% identical to N-succinyldiaminopimelate-aminotransferase (Bordetella pertussis)
Succinyldiaminopimelate transaminase. [EC: 2.6.1.17]

Predicted SEED Role

"N-succinyl-L,L-diaminopimelate aminotransferase alternative (EC 2.6.1.17)" in subsystem Lysine Biosynthesis DAP Pathway (EC 2.6.1.17)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.17

Use Curated BLAST to search for 2.6.1.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8ITA3 at UniProt or InterPro

Protein Sequence (403 amino acids)

>HSERO_RS10805 succinyldiaminopimelate aminotransferase (Herbaspirillum seropedicae SmR1)
VNPLLDQLQPYPFEKLKKLFAGITPDPAYRPISLGIGEPKHPTPAFIQQALIDNLAGLAS
YPATLGSDALRGAIADWLQKRYDIPRPDPATEILPVNGSREALFSLTQTVVDPTRPGALV
MCPNPFYQIYEGSAYLAGAQPYFVNSDPKRNFAPDFSQVPQDVWERVQLLFVCSPGNPTG
AVLTLEDWKELFALSDRYGFVIASDECYSEIYFNEDPPLGGMQAARLLGRDYRRLISFSS
LSKRSNVPGMRSGFVAGDAAILKKFLLYRTYHGAAMSPVIQAASVLAWQDETHVQGNIAK
YVTKFSQVTPLLQEVLEVALPDAAFYLWAKVDKLVNISDTEFAQRLYAEYNVTVLPGSYL
AREAHGVNPGAGRIRMALVAEVEECLEAAQRIVAFTRKLAGQA