Protein Info for HSERO_RS09430 in Herbaspirillum seropedicae SmR1

Annotation: peptidase S49

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 343 transmembrane" amino acids 60 to 78 (19 residues), see Phobius details PF01343: Peptidase_S49" amino acids 157 to 298 (142 residues), 135.8 bits, see alignment E=6.6e-44

Best Hits

KEGG orthology group: K04773, protease IV [EC: 3.4.21.-] (inferred from 100% identity to hse:Hsero_1889)

Predicted SEED Role

"Periplasmic serine proteases (ClpP class)"

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IRS4 at UniProt or InterPro

Protein Sequence (343 amino acids)

>HSERO_RS09430 peptidase S49 (Herbaspirillum seropedicae SmR1)
MSNNESEHPESQPQSTPPAPSSSIPASVRDDKKSGWERDVLEKLALFAVKEQRARRRWGV
FFRIALLAVVVLGVWMAFTFNRIENEPLGPHTALVEIKGAIDSEGQGSAGVVIPALDKAF
AANDSVGVILKINSPGGSPVQAGMINDEITRLRKQYPKKPIYVVVEEVCASGGYYIAAAA
DKIFVNKASLVGSVGVLMDGFGFTGLMDKLGVERRLLTAGENKSFLDPFSPQSPKQREYA
QSMLQEIHQQFIEVVRQGRGARLKETPDTFSGLVWTGSKAVELGLADGFGTVDSVARDEI
KAEDVVDYTQTENLSERVLKKFGVAFGAGFAKTVMSSSLPQLR