Protein Info for HSERO_RS09410 in Herbaspirillum seropedicae SmR1

Annotation: ribonuclease E

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1062 TIGR00757: ribonuclease, Rne/Rng family" amino acids 13 to 423 (411 residues), 529.4 bits, see alignment E=3.2e-163 PF00575: S1" amino acids 37 to 115 (79 residues), 33.3 bits, see alignment 8.1e-12 PF10150: RNase_E_G" amino acids 120 to 389 (270 residues), 328.2 bits, see alignment E=6.1e-102 PF20833: RNase_E_G_Thio" amino acids 401 to 486 (86 residues), 115.4 bits, see alignment E=1.6e-37

Best Hits

Predicted SEED Role

"Ribonuclease E (EC 3.1.26.12)" in subsystem RNA processing and degradation, bacterial or Ribosome biogenesis bacterial (EC 3.1.26.12)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.26.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IRS0 at UniProt or InterPro

Protein Sequence (1062 amino acids)

>HSERO_RS09410 ribonuclease E (Herbaspirillum seropedicae SmR1)
MKRMLFNATQQEELRVAIVDGQKLIDIDIETTGREQRKSNIYKGVITRIEPSLEACFVNY
GEERHGFLPFKEVARSYFKEGIDVRNASIKEALREGQEIIVQVEKEERGNKGAALTSFIS
LAGRYLVLMPNNPRGGGVSRRVEGEDRQELRETMDKLDLPNGMSVIARTAGIGRNVDELQ
WDLNYLMQLWRAIEGAGQSASGAFLIYQESSLVIRAIRDYFQPDIGEILIDTDDIHDQAQ
QFMAHVMPDMVHRVKRYRDDVPLFSRFQIEHQIETAYSRTVPLPSGGAIVIDHTEALVSV
DVNSARATRGSDIETTAFNTNLEAADEVARQLRLRDLGGLIVIDFIDMENSKNQREVEGR
LKDALHHDRARVQMGKISRFGLMELSRQRLRPSLSEGSHVTCPRCNGTGHIRDTESSALQ
VLRIIQEEAMKENSAAIHVQAPVDVAAFLLNEKRGEILKIETRHRVTVIMIPNKHLETPH
YKMERIKHDDPRLDDAQASYTMAEQADTDIGYSKRQKEDVRPRQEAVVKGITPDQPAPIV
ERKAPEPVAAPVPPPTLAPESGLLGKIFSFFRKKPVAPVAAPAPVEAKAPAKREGERNGR
GGDRNGRNRNRNERGDRAERGERAERNGEQRNGRNPAAAELKAGDAAEGKQVRAPRPPRE
PKEGREPREPRELQAQARDGQEVKETRRNEPREAREPREGREGREPREGREPRAPRAPRG
ERKEAKSEEGLPLEAALAAGTAGVAVAAGTAVIASDEAATQVEAAQVEAGEAGEGAETAE
GATEPRRRRRRGGRNRHRRERDENGNLIDNAEAGDSAEGDAAETAEGAEAAIPAFVPVAD
AAAASAQAAVAQASFAASPVPAAEDAPVAESAAKVESGVNSVEAVAAAAAEATEAVFSHQ
PAIEPVAPSIDASFAPAPVEAAVQAPAQAPAASEAPVEVVPVVAAEPVAAPAPVVQQQIS
LLDAVEAAPVVASAPAAPAAPAAPAPQAAPAPAQAAGNGAQWDSLQQMLSQAGLTLATTD
PVKLRAAQEAAAAFVPAPRVPRERKPLPPQSTEPLVQVETRR