Protein Info for HSERO_RS09195 in Herbaspirillum seropedicae SmR1

Annotation: glutathione ABC transporter substrate-binding protein GsiB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 523 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details PF00496: SBP_bac_5" amino acids 78 to 436 (359 residues), 327.2 bits, see alignment E=7.2e-102

Best Hits

KEGG orthology group: K13889, glutathione transport system substrate-binding protein (inferred from 100% identity to hse:Hsero_1843)

Predicted SEED Role

"Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2); Putative hemin-binding lipoprotein" (TC 3.A.1.5.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IRM9 at UniProt or InterPro

Protein Sequence (523 amino acids)

>HSERO_RS09195 glutathione ABC transporter substrate-binding protein GsiB (Herbaspirillum seropedicae SmR1)
MSTTATHKGVSAAKWLAVAALGTTLQFAAAHAFAAKTVTLAVYSTFTTLDPYDANDTLSL
SMAKSFYQGLFGFDKDMKLIPVLAEGYLVSKDGLEYTIRLKQGVKFQDGTVFKADAVKAV
FDRVTNPDNKLKRYNLFNRIAKTEILNDYTVKVVLKEPFSAFINVLAHPSAVMISPTALK
QYGNKDIAFHPVGTGPFKFVEWKQTDYVKVAKFDGYWKPGYPKVDEIIWKPVVDNNARSA
MMQTGEAQFTYPLPYEQADLLKSKSNLDVVAAPSIIQRYMSMNTKQKPFDNPKVREAINY
AINKQALVKVAFNGYAVPMDGVVPQGVDYAYKTGPWPYDVKKAKALLAEAGYPNGFETEL
WSAYTHSTAVKIVQFLQQQLAQVGIKAKIQALEAGQRVERVESWQDPATAPVRLLYIGWS
SSTGEADWALRPLLASESFPPRLYNTAYYKNDKVDADIAKALTLTERKDKEALYKDAQQE
IWKDAPWAFLVTEKLLYARNKNLKGVYVMPDQAIEFENIELVK