Protein Info for HSERO_RS09040 in Herbaspirillum seropedicae SmR1

Annotation: multidrug DMT transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 transmembrane" amino acids 25 to 46 (22 residues), see Phobius details amino acids 52 to 73 (22 residues), see Phobius details amino acids 85 to 104 (20 residues), see Phobius details amino acids 110 to 131 (22 residues), see Phobius details amino acids 139 to 157 (19 residues), see Phobius details amino acids 164 to 184 (21 residues), see Phobius details amino acids 196 to 215 (20 residues), see Phobius details amino acids 227 to 247 (21 residues), see Phobius details amino acids 259 to 277 (19 residues), see Phobius details amino acids 283 to 303 (21 residues), see Phobius details PF00892: EamA" amino acids 23 to 151 (129 residues), 55.2 bits, see alignment E=4.4e-19 amino acids 168 to 297 (130 residues), 53.3 bits, see alignment E=1.7e-18

Best Hits

Swiss-Prot: 47% identical to YDEK_BACSU: Uncharacterized transporter YdeK (ydeK) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_1811)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IRJ7 at UniProt or InterPro

Protein Sequence (306 amino acids)

>HSERO_RS09040 multidrug DMT transporter permease (Herbaspirillum seropedicae SmR1)
MQASSKPVVTATAEGNVARNESRGMWLGLIGVAVFSLTLPFTRIAVAELSPAFVAFGRAV
VAGLCSLALLAWMRAPRPNAQQLRGLVITALGVVVGFPLFSSIAMRYVPAAHGAVVVGLL
PLATALFGALRFGERPSAGFWLSALAGSAIVIAFALRAGGGSFHAADFALFAAVITAAMG
YAEGGRLAQSMGGQNVIAWALVVALPVMLPVSLWLGWQDGLSASAPAWLAFGYVSLFSMF
IGFFFWYKGLALGGIARVGQVQLLQPFMSLLGAAVIAGEALDASNMLFALAVIVVVAIGR
RMAVRR