Protein Info for HSERO_RS08360 in Herbaspirillum seropedicae SmR1

Annotation: multidrug DMT transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 287 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 39 to 56 (18 residues), see Phobius details amino acids 68 to 90 (23 residues), see Phobius details amino acids 96 to 115 (20 residues), see Phobius details amino acids 122 to 145 (24 residues), see Phobius details amino acids 153 to 171 (19 residues), see Phobius details amino acids 183 to 201 (19 residues), see Phobius details amino acids 217 to 237 (21 residues), see Phobius details amino acids 245 to 263 (19 residues), see Phobius details amino acids 269 to 286 (18 residues), see Phobius details PF00892: EamA" amino acids 6 to 136 (131 residues), 47.6 bits, see alignment E=9.8e-17 amino acids 154 to 286 (133 residues), 46 bits, see alignment E=3.1e-16

Best Hits

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_1681)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IQT3 at UniProt or InterPro

Protein Sequence (287 amino acids)

>HSERO_RS08360 multidrug DMT transporter permease (Herbaspirillum seropedicae SmR1)
MPPPPLLAGILVALIWGIQPVISRYGFQHGLTPQDATLVRYLTSGLLMLPYVWRRGLAKA
CGLRWPRALVLFLLSGPLFSLVLVGGVNYAPASHGALIHPALTPLFGMAISRFVFRRDER
FSLWGTVLLVGGLLVVGLHGVMAGGSLAPEGAWRGDLLFVLSAFMWAWYLVLNKTWGLPP
LDAVAMTQVLSLGWVLAVLPWQGPETFAKPWAALALQSLYHGVLVSIVSVALFNWVVARL
GVKAMMLNALSPLFGVLASAWALREPLPPSMLAGAAAIMAGLALSLR