Protein Info for HSERO_RS08290 in Herbaspirillum seropedicae SmR1

Annotation: leucine/isoleucine/valine transporter ATP-binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 234 PF00005: ABC_tran" amino acids 17 to 161 (145 residues), 118.7 bits, see alignment E=3.2e-38

Best Hits

Swiss-Prot: 72% identical to LIVF_SALTI: High-affinity branched-chain amino acid transport ATP-binding protein LivF (livF) from Salmonella typhi

KEGG orthology group: K01996, branched-chain amino acid transport system ATP-binding protein (inferred from 100% identity to hse:Hsero_1666)

MetaCyc: 71% identical to branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF (Escherichia coli K-12 substr. MG1655)
ABC-15-RXN [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]

Predicted SEED Role

"Branched-chain amino acid transport ATP-binding protein LivF (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IQR8 at UniProt or InterPro

Protein Sequence (234 amino acids)

>HSERO_RS08290 leucine/isoleucine/valine transporter ATP-binding subunit (Herbaspirillum seropedicae SmR1)
MLQFDKVHTHYGAIEALHGVSLNVEKGEIVTLIGANGAGKTTLLMTLCGRPRASSGRVIF
EGQDITQLQTHEIMRRGLAISPEGRRVFPSLTVLENLKMGAFFASNEAIEQGIEYVFGLF
PRLKERAAQRAGTMSGGEQQMLAIGRALMSKPRLLLLDEPTLGLAPLVIAQIFDIIRTIR
ESGVTVFLVEQNANKALGVADRGYVLENGHVVMSDTGANLLANSDVRKAYLGHG