Protein Info for HSERO_RS06845 in Herbaspirillum seropedicae SmR1

Annotation: phosphodiesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 591 PF13185: GAF_2" amino acids 24 to 152 (129 residues), 34 bits, see alignment E=6.6e-12 PF01590: GAF" amino acids 25 to 155 (131 residues), 68 bits, see alignment E=2.5e-22 PF00990: GGDEF" amino acids 164 to 314 (151 residues), 24.7 bits, see alignment E=3.6e-09 PF00563: EAL" amino acids 349 to 577 (229 residues), 239.9 bits, see alignment E=5.2e-75

Best Hits

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_1364)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IP60 at UniProt or InterPro

Protein Sequence (591 amino acids)

>HSERO_RS06845 phosphodiesterase (Herbaspirillum seropedicae SmR1)
LPLDAAEQQRLAVLDAYCLLDTQPDPLCDMITELATRLFDVEIALVSLVAEHRQWFKSRR
GLDAPGTPRSQSFCAHAIVQAQTMVIPDARQDERFAGNPLVLGEPGIRFYAGAALRTADG
VALGTLCLIGKSPRSQFSEVDQDRLERLAAIVMARLDMLRMGSYVDSLTSLPNRSRLVAD
VQLMQAHATGLAGLDELPRRLAAVAVDVCDHTYLTDMVKALGWDYVEGFLIQAKERLCQA
LGEMALYRIGATSFAYLDRCDRWQDQADRIRQAFAATVEHQGIPHHLEVSVGIVPLSQCP
DAAELVPSLLTAADVARADGHLQCQYEQPLGQMQKHSFELLSSIPAALLSTDQLWLEFQP
KVSLSTGRCAGVEALLRWRHPIHGVISPALFIPLAEKTALIRQVTLWVLQRGIEQATAWA
RRGVAIPVAINVSARDFDNDDLLQLLGRLLEQHRIPAGLIEIEFTESAMSRNPEKLYGRI
QEIKRLGVKVAIDDFGAGFSNLSYLKHIPADYLKLDQSFILRMESDYSDQQIVPSMIHLG
QRLGFAVVAEGVENEKTRRILQHLGCDFGQGFGIARPMNAADCWDWIGARQ