Protein Info for HSERO_RS06145 in Herbaspirillum seropedicae SmR1

Annotation: NrdR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 159 TIGR00244: transcriptional regulator NrdR" amino acids 1 to 146 (146 residues), 200.8 bits, see alignment E=5.5e-64 PF03477: ATP-cone" amino acids 50 to 136 (87 residues), 64.8 bits, see alignment E=4.3e-22

Best Hits

Swiss-Prot: 84% identical to NRDR_JANMA: Transcriptional repressor NrdR (nrdR) from Janthinobacterium sp. (strain Marseille)

KEGG orthology group: K07738, transcriptional repressor NrdR (inferred from 100% identity to hse:Hsero_1224)

Predicted SEED Role

"Ribonucleotide reductase transcriptional regulator NrdR" in subsystem Ribonucleotide reduction

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8INS0 at UniProt or InterPro

Protein Sequence (159 amino acids)

>HSERO_RS06145 NrdR family transcriptional regulator (Herbaspirillum seropedicae SmR1)
MKCPFCNHEDTPVLDTRLSEDGHSIRRRRRCGNCDKRFTTYERIELTLPVIVKKNGSRTE
FDPAKLRGSLMLALRKRPVSAEAVDMAIQSIQDKLLQSGEREVMSGQIGELVMRELKRLD
KIAYIRFASVYKSFEDVAEFQDAIAEVGQERKGAKRRDD