Protein Info for HSERO_RS04990 in Herbaspirillum seropedicae SmR1
Annotation: molecular chaperone GroEL
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 87% identical to CH60_METFK: 60 kDa chaperonin (groL) from Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875)
KEGG orthology group: K04077, chaperonin GroEL (inferred from 100% identity to hse:Hsero_0996)MetaCyc: 73% identical to chaperonin GroEL (Escherichia coli K-12 substr. MG1655)
Non-chaperonin molecular chaperone ATPase. [EC: 3.6.4.10, 5.6.1.7]
Predicted SEED Role
"Heat shock protein 60 family chaperone GroEL" in subsystem GroEL GroES or Staphylococcal pathogenicity islands SaPI
Isozymes
No predicted isozymesUse Curated BLAST to search for 3.6.4.10 or 5.6.1.7
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See D8J0V8 at UniProt or InterPro
Protein Sequence (549 amino acids)
>HSERO_RS04990 molecular chaperone GroEL (Herbaspirillum seropedicae SmR1) MAAKQVIFGDEARAKVVNGVNILANAVKVTLGPKGRNVVLERSFGAPTVTKDGVSVAKEI ELKDKLENMGAQLVKEVASKTSDNAGDGTTTATVLAQAIVREGFKYVAAGFNPTDLKRGI DKAVTAIVGEVKNLAKPTTTSKEIAQVGSISANSDADIGDIIAKAMEKVGKEGVITVEDG KSLENELDIVEGMQFDRGYLSPYFINNQEKQIVALDNPFILLFDKKISNIRDLLPVLEQV AKAGRPLLIVAEDVEGEALATLVVNNIRGILKTAAVKAPGFGDRRKAMLEDIAILTGGQV IAEEVGLTLEKATLAELGQAKRVEIGKENTTIIDGNGEAAGIEARVAMIRTQIGEATSDY DREKLQERVAKLAGGVALIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALL RARANVKDLKGDNPDQEAGIKIVLRAIEEPLRQIVFNAGDEPSVVVNKVLEGSGNFGYNA SNGTYGDLVELGVLDPAKVTRSALQNAASVASLILTTDALVAEVAEDKPAGMPGGMGGMG GMGGMDGMM