Protein Info for HSERO_RS04130 in Herbaspirillum seropedicae SmR1

Annotation: proline/betaine transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 428 transmembrane" amino acids 18 to 41 (24 residues), see Phobius details amino acids 53 to 76 (24 residues), see Phobius details amino acids 88 to 105 (18 residues), see Phobius details amino acids 111 to 132 (22 residues), see Phobius details amino acids 157 to 180 (24 residues), see Phobius details amino acids 189 to 208 (20 residues), see Phobius details amino acids 236 to 256 (21 residues), see Phobius details amino acids 276 to 296 (21 residues), see Phobius details amino acids 306 to 325 (20 residues), see Phobius details amino acids 333 to 355 (23 residues), see Phobius details amino acids 371 to 393 (23 residues), see Phobius details amino acids 399 to 419 (21 residues), see Phobius details PF00083: Sugar_tr" amino acids 18 to 225 (208 residues), 90.5 bits, see alignment E=1.2e-29 amino acids 219 to 410 (192 residues), 24.8 bits, see alignment E=9.9e-10 PF07690: MFS_1" amino acids 22 to 369 (348 residues), 110.7 bits, see alignment E=7.7e-36 amino acids 285 to 425 (141 residues), 34.1 bits, see alignment E=1.5e-12

Best Hits

Swiss-Prot: 36% identical to CITA_ECOLX: Citrate-proton symporter (citA) from Escherichia coli

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_0825)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8J007 at UniProt or InterPro

Protein Sequence (428 amino acids)

>HSERO_RS04130 proline/betaine transporter (Herbaspirillum seropedicae SmR1)
MNHPVQGTDPKTQRRAVIAATLGNVLEIYDFIIFGIFAVAISKTFFPSGDEYAALMFTFM
TFAAGFVVRPIGALVLGQYADKVGRKKALSFTLILMAIGTVIPALCPSYDSIGIAATVIL
VFGRLLQGFSAGGEIGSNVAMLVENASSRNRALFCSFQQMAQGGGVLLGGIVGYVIAVVY
GQERMLQDYWRLAFFVGLVIGPVGWYIRRVLPETPEFERSKKKESVDSFLEGVKANFGRI
LIGIAIMIFWTVATQVSNYFTTYAVRELHMPVASTYLGQISSGLTLLAICPLVGMLADRI
GPYKPMAFGAALAGVLAYPLFKMLVATPTLPTLLLVQIAISVTLGLYAACAPLVMSDIFP
TRYRATGIGTSYALGVMIFGGLTPMIVTTLIQISGDKLIIGLYLTAAALLSLALIGALVR
MQRKPVPA