Protein Info for HSERO_RS02725 in Herbaspirillum seropedicae SmR1

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 845 TIGR00229: PAS domain S-box protein" amino acids 141 to 263 (123 residues), 38.9 bits, see alignment E=4.4e-14 PF00989: PAS" amino acids 145 to 255 (111 residues), 27.8 bits, see alignment E=8.9e-10 PF08448: PAS_4" amino acids 152 to 259 (108 residues), 44.4 bits, see alignment E=7e-15 PF13185: GAF_2" amino acids 280 to 416 (137 residues), 34.6 bits, see alignment E=8.5e-12 PF01590: GAF" amino acids 281 to 417 (137 residues), 44.5 bits, see alignment E=9.5e-15 PF00512: HisKA" amino acids 469 to 533 (65 residues), 34.8 bits, see alignment 5.6e-12 PF02518: HATPase_c" amino acids 577 to 697 (121 residues), 74.8 bits, see alignment E=3.1e-24 PF00072: Response_reg" amino acids 723 to 834 (112 residues), 63.4 bits, see alignment E=8.5e-21

Best Hits

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_0547)

Predicted SEED Role

"Chemotaxis protein methyltransferase CheR (EC 2.1.1.80)" in subsystem Bacterial Chemotaxis (EC 2.1.1.80)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.80

Use Curated BLAST to search for 2.1.1.80

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IYA6 at UniProt or InterPro

Protein Sequence (845 amino acids)

>HSERO_RS02725 histidine kinase (Herbaspirillum seropedicae SmR1)
MSTALSPDRLPALPPEAFFALDPQWRFVFLDSPAQALLNPHGQDLLGRPIWQACPELLGS
PLEECLRAVQADQRSRDAVLIHPHHQPGPAYAVSCYAGAHGLSVKLRAIAAQPAAEHGLQ
QTRLRHEAVAELARLTDESERRRRFYETFFATTPDLAYAWDLEHRFTYANRVLLQMWGKT
WDEAIGKTCLELGYEPWHAEMHSREIEQVRATKRPVRGDVPFNGTFGRRIYDYIIFPVLG
PDGEVEAVAGTTRDVTDRKHSEARQHALLHLADAIRATDSPQDIASAAAHIIGEALTARW
VSFHTLGPQRQCQDLGQWRFHRDDDAERGLQAHARRPLQRVLEQGHPMLVADVSSDARTV
ALADEQRALGVVSFMDVPVLAQDQPVALVQVSSDAPRVWTENELAIVREVSERACAAFER
IRNQRALAESEARLRAINESLEAEVSARTRELMATEEALRHSQKIEAIGQLTGGLAHDFN
NLLGGISGSLDLMRVRLVQGRGEELLRYVELAARSTQRAASLTQRLLAFARRQTLAPKPT
RVNALISGMEELIRRTIGPAIVLEVVGAGGLWPTFVDGPQLESALLNLCINARDAMPGGG
RLTIETANKWLDDRWAHERDLPPGQYVCISVTDSGVGMPPDVLARAFDPFFTTKPIGAGT
GLGLSMVYGFARQSGGQVRLYSEVGQGTTVSIYLPRHQHDGDEQDEADALDETAAGDGNG
EVVLVVDDEASIRMLVAEILSDAGYDVLQAEDGPGALRILQSKQRIDLLITDVGLPGGLN
GRQVADAGRAARPDLHVLFITGYAENAAFDNGHLERGMQLMTKPFKMEALARRVQSILES
RVAPN