Protein Info for HSERO_RS02515 in Herbaspirillum seropedicae SmR1

Annotation: enzyme with a TIM-barrel fold protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 270 TIGR00044: pyridoxal phosphate enzyme, YggS family" amino acids 31 to 257 (227 residues), 190.9 bits, see alignment E=1.3e-60 PF01168: Ala_racemase_N" amino acids 34 to 257 (224 residues), 74.4 bits, see alignment E=5.7e-25

Best Hits

Swiss-Prot: 42% identical to PLPHP_AQUAE: Pyridoxal phosphate homeostasis protein (aq_274) from Aquifex aeolicus (strain VF5)

KEGG orthology group: K06997, (no description) (inferred from 100% identity to hse:Hsero_0507)

Predicted SEED Role

"Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IXF1 at UniProt or InterPro

Protein Sequence (270 amino acids)

>HSERO_RS02515 enzyme with a TIM-barrel fold protein (Herbaspirillum seropedicae SmR1)
MSDPQFPEDESTAIRHDMHGRWPAAASLDEFRANLAAVHRRIAAACERAGRPASSVRLLP
VSKTKPESSIRLAYAAGCCLLGENKPQEACHKWEATQDLSGLQWSVIGHLQTNKAKLVAR
FAAEFQALDSLRVAQALERRLQQEGRGLDVFVQVNTSGEASKYGLAPEEVAPFLRQLHAY
PALRLRGLMTLAVFSPDPARVRPCFSLLRNLRERLRQDVPAGAQLDELSMGMSGDYEIAI
EEGATVVRVGQALFGARALPDSHYWPSPDN