Protein Info for HSERO_RS02455 in Herbaspirillum seropedicae SmR1

Annotation: UDP pyrophosphate phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 284 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details transmembrane" amino acids 51 to 68 (18 residues), see Phobius details amino acids 88 to 107 (20 residues), see Phobius details amino acids 113 to 134 (22 residues), see Phobius details amino acids 196 to 216 (21 residues), see Phobius details amino acids 228 to 249 (22 residues), see Phobius details amino acids 261 to 283 (23 residues), see Phobius details TIGR00753: undecaprenyl-diphosphatase UppP" amino acids 9 to 268 (260 residues), 247.3 bits, see alignment E=1e-77 PF02673: BacA" amino acids 9 to 270 (262 residues), 295.9 bits, see alignment E=1.6e-92

Best Hits

Swiss-Prot: 73% identical to UPPP_JANMA: Undecaprenyl-diphosphatase (uppP) from Janthinobacterium sp. (strain Marseille)

KEGG orthology group: K06153, undecaprenyl-diphosphatase [EC: 3.6.1.27] (inferred from 100% identity to hse:Hsero_0492)

Predicted SEED Role

"Undecaprenyl-diphosphatase (EC 3.6.1.27)" (EC 3.6.1.27)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.27

Use Curated BLAST to search for 3.6.1.27

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IXD7 at UniProt or InterPro

Protein Sequence (284 amino acids)

>HSERO_RS02455 UDP pyrophosphate phosphatase (Herbaspirillum seropedicae SmR1)
MDTLLALKALIMGIVEGLTEFLPISSTGHLILANSLLQFTGPDLSKEKADVFEIVIQAGA
ILAVCWEYRVRIATVLTGMFTDRKAQRLVVNLIIAFLPAAILGFLFSRRIKEVLFNPVSV
AIAFIVGGLIILWVERRNKDRMSMASARVETVDDMTPLDALKVGIAQAFALIPGTSRSGA
TIIGGMMFGLSRKAATEFSFFLAIPTLFAATIYSLYKERALLSAADVPLFTVGTVAAFVS
AFLCVRWLLRYISSHDFTIFAWYRIIFGIIVLVTAYTGVVAWVE