Protein Info for HSERO_RS01535 in Herbaspirillum seropedicae SmR1

Annotation: phosphohydrolase with GAF sensor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 552 PF13185: GAF_2" amino acids 35 to 202 (168 residues), 43.1 bits, see alignment E=1e-14 PF01590: GAF" amino acids 38 to 201 (164 residues), 53.5 bits, see alignment E=7.7e-18 PF01966: HD" amino acids 234 to 315 (82 residues), 31 bits, see alignment E=5.4e-11 PF13487: HD_5" amino acids 400 to 516 (117 residues), 116.5 bits, see alignment E=2.3e-37

Best Hits

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_0310)

Predicted SEED Role

"Chemotactic transducer-related protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8IW38 at UniProt or InterPro

Protein Sequence (552 amino acids)

>HSERO_RS01535 phosphohydrolase with GAF sensor (Herbaspirillum seropedicae SmR1)
MSPFSHIPAAERHRNIAYRLERLTELCRELGSSRDIPLLLERILLTAKDITQADGGTLYR
INEGGDSLRFYISVNDTLKMHQGGSSGKAISIPDIALRLPDGQPNLSAVAAYAANTRKSV
NIADVYQVSSGFNFNGMRLFDEKYGYQSKSFLTVPMEDHEGELVGVLQLINAIDPATGAP
LPFSETDQHFIEALASQAAMAMTNQQLIQRLEQLFESLIRLINIGIGEKSPHTGRHCEQV
PELAMMLAEAAHNATEGPLADFHMSEADRRELWLAALLHDCGKISTPTHIVEKATKLETI
FDRIHLVETRIEVLKRDAEIRVLQEKLALGAALDAQRAAELDAGLAAELAQLDLERAFLR
KINVGTEGMRPEDQQRVLDIAQRSWRGPDGQLRPLLDEEESANLRIRAGTLNDAERQIIN
NHIVITIKMLESLPWPKQLARVTEFAGGHHERMDGKGYPKGLTREQMSVQARIMAVADIF
EAVTAADRPYKRGNTLNEAVEILAGFKARDHIDPDLFDLFVRERIYEKYAEKFMHPSQID
EVDLSRIPGFGA