Protein Info for HSERO_RS00540 in Herbaspirillum seropedicae SmR1

Annotation: hemin transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 381 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF06228: ChuX_HutX" amino acids 51 to 187 (137 residues), 104.1 bits, see alignment E=5.5e-34 amino acids 243 to 374 (132 residues), 91.5 bits, see alignment E=4.4e-30 PF05171: HemS" amino acids 55 to 191 (137 residues), 84.9 bits, see alignment E=4.6e-28 amino acids 246 to 378 (133 residues), 108.8 bits, see alignment E=1.9e-35

Best Hits

KEGG orthology group: K07225, putative hemin transport protein (inferred from 100% identity to hse:Hsero_0108)

Predicted SEED Role

"Hemin transport protein HmuS" in subsystem Heme, hemin uptake and utilization systems in GramPositives or Hemin transport system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8ITZ3 at UniProt or InterPro

Protein Sequence (381 amino acids)

>HSERO_RS00540 hemin transporter (Herbaspirillum seropedicae SmR1)
MKHRSAPTLLLPAALTLALALAGCAANPPTLSQRWTQLQQAQPRLHLREAAHQLGVSEAE
LLASDANWQATRLTSDARDLQALYERLAELGRIKAVIRNDDVMLERTGAVTPARRDEQGR
VVPGTGLAGGPIDLRIGGVQWGSAFAVAQPGRDGKALRSLQFFDQHGQAIHKIYLDNDEH
IAAYERLVAEFRIAGQPAPLIALPAPTQPPADVRGTASAADVAQLRQAWTKLTDVHQFPR
LLRELKLSREQALQLIGDDSAWRISAQGLQLLMDDARARRQPIMAFVSQGGMTQIYSGMI
DRSSNSGAWYEVLGEDFRLKVRSATIDHGWVVRRPTDHGMVTSVEFYDAAGRQLVNFFSR
RDRGQPETAQWRRMVEALPRS