Protein Info for HSERO_RS00325 in Herbaspirillum seropedicae SmR1

Annotation: multidrug DMT transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 281 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 30 to 50 (21 residues), see Phobius details amino acids 59 to 80 (22 residues), see Phobius details amino acids 112 to 130 (19 residues), see Phobius details amino acids 142 to 160 (19 residues), see Phobius details amino acids 172 to 191 (20 residues), see Phobius details amino acids 211 to 231 (21 residues), see Phobius details amino acids 237 to 256 (20 residues), see Phobius details amino acids 263 to 280 (18 residues), see Phobius details PF00892: EamA" amino acids 6 to 129 (124 residues), 35 bits, see alignment E=7.3e-13 amino acids 144 to 277 (134 residues), 46.2 bits, see alignment E=2.6e-16

Best Hits

KEGG orthology group: None (inferred from 100% identity to hse:Hsero_0066)

Predicted SEED Role

"Permeases of the drug/metabolite transporter (DMT) superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See D8ITV5 at UniProt or InterPro

Protein Sequence (281 amino acids)

>HSERO_RS00325 multidrug DMT transporter permease (Herbaspirillum seropedicae SmR1)
MNIAVIALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWF
YIILSGLLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGI
LLVSLGIVSLADLRAMRSREHLAGPLAAFATGAFIAAYTITDGIGARLAGDAMSYAGWLF
VLDSIALAVIYQRRHGRWPIALGRRETWTGLGGGVMSLLAYGIVIWAVTLAPMGMVSALR
ETSVLFALLIGALFLGERLTLRRVLSGVVIVAGTIVLGTHH