Protein Info for HMPREF1078_RS17375 in Parabacteroides merdae CL09T00C40

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 406 transmembrane" amino acids 21 to 42 (22 residues), see Phobius details amino acids 280 to 307 (28 residues), see Phobius details amino acids 327 to 357 (31 residues), see Phobius details amino acids 367 to 389 (23 residues), see Phobius details PF12704: MacB_PCD" amino acids 22 to 245 (224 residues), 169.8 bits, see alignment E=1e-53 PF02687: FtsX" amino acids 286 to 399 (114 residues), 81.7 bits, see alignment E=4.5e-27

Best Hits

KEGG orthology group: K02004, (no description) (inferred from 92% identity to pdi:BDI_3355)

Predicted SEED Role

"ABC transporter, permease protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (406 amino acids)

>HMPREF1078_RS17375 ABC transporter permease (Parabacteroides merdae CL09T00C40)
MNGTNLIKIAVRALANNKLRGFLTMLGIIIGVASVITMLAIGQGSKRSIQAQISEMGSNM
IMIHPGADVRGGVRQDASAMETLKLQDYEDIVDETRFVSAVSPSVNSSGQAIYGANNAPT
TVYGISPDYLEIRRYKVEDGDMFTEQDIQTAAKVCVVGKTVVDNLFPDGSNPVGKVIRFQ
KLPFRIVGVLESKGYNSMGMDQDDLILAPYTTIQKKVLAITHLQGITCSALKEEYTDQAI
DEISEILRRNHKLKESDDDDFTIRSQQELSTMLTSTTDMMTVLLAAVAGISLLVGGIGIM
NIMYVSVTERTREIGLRMSIGAKGIDILAQFLIESILISVTGGLIGVVFGVGAALVVNGV
AHFPIYIQPWSVILSFAVCTVTGVFFGWYPAKKAAQLDPIEAIRYE