Protein Info for HMPREF1078_RS17255 in Parabacteroides merdae CL09T00C40

Annotation: HAMP domain-containing sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 384 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 142 to 164 (23 residues), see Phobius details PF14501: HATPase_c_5" amino acids 281 to 359 (79 residues), 24.4 bits, see alignment E=2.3e-09 PF02518: HATPase_c" amino acids 282 to 381 (100 residues), 80 bits, see alignment E=1.8e-26

Best Hits

KEGG orthology group: None (inferred from 77% identity to pdi:BDI_2438)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (384 amino acids)

>HMPREF1078_RS17255 HAMP domain-containing sensor histidine kinase (Parabacteroides merdae CL09T00C40)
MKSIYDSRQRLKFVFIFTAILIAIASLVVSDMLIKDLAQEERQKMEVWAEATRLTASKNT
AVDLSLVLKILEGNTTIPVVLCNDKDSIMFVKNISFPENDVEEFKKVKVKELKSKNTIVI
DMEDGTFQYVYYDDSVILKRLLIYPYAQLTVVFVFIVIAFLALASTKKAEQNKVWVGLSK
ETAHQLGTPISSLIAWVEYLRTKDIDSSLLNEMEKDVKRLETIAERFSKIGSNPDPVPVD
INNSIRSALSYMSTRISSKVKIYTHLTDGPVPVLMNDSLFAWVIENLTKNAVDAMEGQGE
ITFQVEERDKVVRIDVTDTGKGIAKSKFKTVFNPGYTTKKRGWGLGLSLVKRIIESYHGG
RIFVKSSEVGKGTTFRIELRKYKG