Protein Info for HMPREF1078_RS16730 in Parabacteroides merdae CL09T00C40

Annotation: acyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 191 PF00132: Hexapep" amino acids 15 to 49 (35 residues), 46.8 bits, see alignment 1.5e-16 amino acids 103 to 137 (35 residues), 28.6 bits, see alignment 8.5e-11 PF14602: Hexapep_2" amino acids 35 to 67 (33 residues), 27 bits, see alignment 2.9e-10 amino acids 103 to 137 (35 residues), 24.1 bits, see alignment 2.4e-09

Best Hits

Swiss-Prot: 55% identical to WBPD_PSEAE: UDP-2-acetamido-3-amino-2,3-dideoxy-D-glucuronate N-acetyltransferase (wbpD) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: None (inferred from 82% identity to pdi:BDI_2184)

MetaCyc: 55% identical to UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase monomer (Pseudomonas aeruginosa PAO1)
RXN-13589 [EC: 2.3.1.201]

Predicted SEED Role

"2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89)" in subsystem Lysine Biosynthesis DAP Pathway (EC 2.3.1.89)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.1.201 or 2.3.1.89

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (191 amino acids)

>HMPREF1078_RS16730 acyltransferase (Parabacteroides merdae CL09T00C40)
METYKAHETAVIDPGCTIGDGTHIWHFSHIMPGCTIGRNCNIGQNVVISPLVVLGNNVKV
QNNVSVYTGVTCGDDVFLGPSCVFTNVVNPRSAVSRKDQYLKTHVGKGASIGANATIVCG
HTIGEYAMIGAGAVVTKDIPPYALVVGNPSRQIGWVSEYGHRLSFNEKGIATCSESNQQY
LLEGGIVTRIS