Protein Info for HMPREF1078_RS15950 in Parabacteroides merdae CL09T00C40

Annotation: FAD-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 814 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details PF07992: Pyr_redox_2" amino acids 2 to 298 (297 residues), 215.4 bits, see alignment E=6e-67 PF13738: Pyr_redox_3" amino acids 63 to 282 (220 residues), 40.6 bits, see alignment E=9.9e-14 PF00070: Pyr_redox" amino acids 152 to 229 (78 residues), 65 bits, see alignment E=3.6e-21 PF02852: Pyr_redox_dim" amino acids 332 to 433 (102 residues), 39.7 bits, see alignment E=2.6e-13 PF00581: Rhodanese" amino acids 470 to 544 (75 residues), 60.8 bits, see alignment E=7.7e-20 PF01206: TusA" amino acids 577 to 645 (69 residues), 68.3 bits, see alignment E=2.1e-22 PF13686: DrsE_2" amino acids 661 to 813 (153 residues), 207.8 bits, see alignment E=4.5e-65

Best Hits

KEGG orthology group: None (inferred from 59% identity to bth:BT_2434)

Predicted SEED Role

"CoA-disulfide reductase (EC 1.8.1.14) / Disulfide bond regulator" (EC 1.8.1.14)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.8.1.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (814 amino acids)

>HMPREF1078_RS15950 FAD-dependent oxidoreductase (Parabacteroides merdae CL09T00C40)
MNYLIIGGVAGGATVAARLRRMDEKANIILFERGKYVSYANCGLPYYIGDTINNREKLFV
QTAKGFTDRFRIDIRTEQEVTAIRPDKKEVEIKNLSTGETYTETYDKLVLSPGAEPLRPG
IEGIGSKKIFTLRNVPDTDTIKNYVNTENPKRAIVVGGGFIGLEMAENLHDLGIQVDVVE
MANQVMAPLDFSMAAIVHRQLTDKGVGLHLEDGVSRFEEKDGGVTVHLRSGKQIATDMVL
LSIGVRPETKLAKDAGLAIGERGGIAVNDYMQTSDADIYALGDAVEVRHLVTGQPALIPL
AGPANKQGRIVADNIVFGNKKKYPGSIGTSIAKVFDLTVAAAGANAKLLQQNNIPYISSY
THGASHAGYYPGAVPLSIKILFAPENGKLLGAQIVGFNGVDKRIEMLAQVIQRGGTVHDL
AELEHAYAPPYSSAKDPVNMAGFVAENILNKKSRIIQWRELAELPADTIRIDVRTHDEYK
LGTIPGFINIPVDELREHLDELPKEKPIVVTCAVGLRGYLAYRILVQNGFKHVRNLSGGY
KTWSVATAPIKEIVSHKPEIPESTSYGNSDSQINLLKVDACGLMCPGPVMQLKKNYEALK
IGEQLQITATDQAFGKDVTSWCKMTGAELVALENKNGVVAATIRKQEKTASCEISRNNAD
NKTLIVFSDDLDKALASFVIANGAASTGKKVTMFFTFWGLNVIKKQHKPTVTKDIFGKMF
GWMLPTHSGKLKLSKMNMGGAGSWMMRLIMKRKRIDSLESLIQQAIDNGVEMIACTMSMD
VMGVQKEELMDNVTLGGVASYLERAEEANVNLFI