Protein Info for HMPREF1078_RS15865 in Parabacteroides merdae CL09T00C40

Annotation: DUF5686 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 726 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF18939: DUF5686" amino acids 47 to 695 (649 residues), 422.9 bits, see alignment E=1.2e-130

Best Hits

KEGG orthology group: None (inferred from 68% identity to pdi:BDI_0283)

Predicted SEED Role

"FIG00898388: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (726 amino acids)

>HMPREF1078_RS15865 DUF5686 family protein (Parabacteroides merdae CL09T00C40)
MLKKYFYIIILLFTAVNALADPDGSYGNLLLLGRSPKTVSSQQGDSIMRKVIEQADKYKT
VVSRYEAEIYIKGKTEILKQNILMRFAHHLFPVDRKNKDMIFEMVSHSKFNAPNNYLHSF
EAINGNSIPNGAKQQEVLTFLNLNVYSPTIYNEGIIMPVAHEAFKYYNFNLESIETTGNL
KIYQIRFMPKLWSQKLICGDLYITDKDWHIDKIDLNGRFSFAEFNLVMTFGRDYRHFILP
QKADLFLRYHVLGNAIASYYHTSFKYEAVEWVEEDYEDKKHHSLDLTGYYQLSSDTIPII
SDSSYWKNKRDIPLTQEEETKYEKTSIRTTQANDTSNIRKYLKITERLTNTINLDYKTTR
LKYSGILNPFQLGYSGRNGITYRQQLRFSKTFKKDRQLRFRPEVGFVFKRKELFFKFEGD
WEYLPEKQGALSLSLGNTNQGYSSKIMNEINEQLKDSTFNFENLDLEYFKHYYIELKNQI
ELFNGFQMITGISYHRRIPTRKSAIDPGDGVTEIINENYHDFIPTIGFSYTPRQYYWMDG
YRKEYLYSYYPTISIEFGRAIPGVWKSSGNYGRVEADIHQSIYLGLSRRFNYHISGGLYT
AQKSTYFADYRYFTRHNFPESWGGDDFGGVFHQLGSVWFNASDKYVQAHAMYESPFMLFQ
LFKPEATKHIISERFYLSQLWMPVKPSYTEIGYGFGNHIFNVAAFVGFDKLKYDGIGFKF
AFELFQ