Protein Info for HMPREF1078_RS15690 in Parabacteroides merdae CL09T00C40

Annotation: response regulator transcription factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 233 PF00486: Trans_reg_C" amino acids 152 to 226 (75 residues), 59 bits, see alignment E=2e-20

Best Hits

Swiss-Prot: 46% identical to RPRY_BACFR: Transcriptional regulatory protein RprY (rprY) from Bacteroides fragilis (strain YCH46)

KEGG orthology group: None (inferred from 47% identity to bsa:Bacsa_1013)

Predicted SEED Role

"Transcriptional regulatory protein rprY"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (233 amino acids)

>HMPREF1078_RS15690 response regulator transcription factor (Parabacteroides merdae CL09T00C40)
MNDLFNILIFSKDYNQGVIIQDYIKAIGYNSQVFDQEEAAYEGFLSRNFTLCIINHDIDT
KETRTLAAMIKSSENIIPVVFLCEHPTREEIALLFSFHADDVIRKPLDTDILQARIKAVQ
SRYQPQRKKEVRTYIFGKFKFDLQKQILSIEGKTTKLTTKEADLLTLLCQHANNMVDRMH
ALQIIWRSDNYFSARSMDVYITKLRKLLQDDPTIKIINVHGKGYKLSTRENDN