Protein Info for HMPREF1078_RS15450 in Parabacteroides merdae CL09T00C40

Annotation: Fe-S cluster domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 336 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF04060: FeS" amino acids 42 to 64 (23 residues), 32.7 bits, see alignment (E = 2.8e-11) PF12838: Fer4_7" amino acids 140 to 185 (46 residues), 30.4 bits, see alignment 2.3e-10 amino acids 218 to 262 (45 residues), 37.1 bits, see alignment 1.9e-12 PF13187: Fer4_9" amino acids 140 to 185 (46 residues), 30.5 bits, see alignment 1.7e-10 amino acids 218 to 263 (46 residues), 36.7 bits, see alignment 1.9e-12 PF12837: Fer4_6" amino acids 164 to 186 (23 residues), 30.3 bits, see alignment (E = 1.5e-10) amino acids 240 to 263 (24 residues), 29.4 bits, see alignment (E = 3e-10) PF00037: Fer4" amino acids 164 to 187 (24 residues), 34.3 bits, see alignment (E = 7.8e-12) amino acids 217 to 235 (19 residues), 26.3 bits, see alignment (E = 2.8e-09) amino acids 242 to 263 (22 residues), 30.7 bits, see alignment (E = 1.1e-10) PF12797: Fer4_2" amino acids 164 to 182 (19 residues), 28.9 bits, see alignment (E = 4e-10) PF13237: Fer4_10" amino acids 165 to 230 (66 residues), 27.3 bits, see alignment E=1.6e-09 amino acids 216 to 259 (44 residues), 30 bits, see alignment 2.4e-10 PF13534: Fer4_17" amino acids 170 to 230 (61 residues), 29.1 bits, see alignment E=6.6e-10

Best Hits

KEGG orthology group: None (inferred from 84% identity to pdi:BDI_0516)

Predicted SEED Role

"Electron transport complex protein RnfB" in subsystem Na(+)-translocating NADH-quinone oxidoreductase and rnf-like group of electron transport complexes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (336 amino acids)

>HMPREF1078_RS15450 Fe-S cluster domain-containing protein (Parabacteroides merdae CL09T00C40)
MILIAVISLGAIGAIGAVFLYAASKKFEVYEDPRIAQVQEVLPGANCGGCGYPGCGGFAT
ACVKADTLNGLLCPVGGAPVMGKVATILGKEAASAEPMVAVVRCNGTCAARPRTNQYDGV
QSCAIASTLYGGETGCSFGCLGYGDCVAACNFDAIHINLETGLPEVDEDKCTSCGACVKA
CPKNIIELRKKGPKSRRVFVSCVNKDKGGVAKKACANACIGCGKCAKECPFEAITVENNV
AYIDYTKCRLCRKCVAVCPTGAIHELNFPPRKEAAPAVDADKIKPATAPKPAAPKADAPK
TEVPKKESPKAEAPTANATPNAATPKVETKEETIQK