Protein Info for HMPREF1078_RS15160 in Parabacteroides merdae CL09T00C40

Annotation: glycoside hydrolase family 127 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 679 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF07944: Glyco_hydro_127" amino acids 91 to 417 (327 residues), 112.9 bits, see alignment E=1.8e-36 PF20736: Glyco_hydro127M" amino acids 431 to 530 (100 residues), 71.2 bits, see alignment E=6.6e-24

Best Hits

KEGG orthology group: None (inferred from 77% identity to pdi:BDI_3334)

Predicted SEED Role

"Putative glycosyl hydrolase of unknown function (DUF1680)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (679 amino acids)

>HMPREF1078_RS15160 glycoside hydrolase family 127 protein (Parabacteroides merdae CL09T00C40)
MNKLKKIFLTAVATLTVATVSAAGEEPAAESYRNNRHPLLQKDYIQLPLGTIRAEGWMHD
QLTRMRDGMTGHLDKVYTKVMGPRNGWLGGDGDVWERGPYWIDGLLPLAYLLNDQALIEK
VQPWIEWTLASQKPNGYFGPDTDRDYEPGLQRNNAQDWWPKMVMLKVMQQYYTATQDRRV
IDFMTRYFRYQLDELPKNPLGKWTFWGEQRGGDNLMVVYWLYNITGDKFLLDLGELIHKQ
TFNWTDIFLNQNHLRRQHSLHCVNLAQGFKEPIVYYQQGKDSKQIQATRQAVNDIRHTIG
LPTGLWGGDELLRFGKPTTGSELCTAVEMMYSLETILEVTGDMQWADYLERVAYNALPTQ
VTDDYSARQYYQQTNQIAVTREWREFSTPHDDTDLLFGELTGYPCCTSNLHQGWPKFVQN
LWYATADNGLASLLFAPSQVTARVAGGIEVNLKEETAYPFEETVRYHVSFTDKKVKKVFF
PFHLRIPGWCKQPVVKLNGKPLTVDAYPGTVTRINREWKEGDILSLELPMEVTVSRWYEN
SAVVERGPLVYALKMNEKWEKKAFESDKSDVYGKWYYEVTSDSPWNYALPARSFSPDRIK
DAFTVEKSDITTPYPWNVENAPIRIKTKAMRLNGWTQVRGSAGPVPYYTQQGKDFGDEET
IELIPYGCTTLRITEFPVR