Protein Info for HMPREF1078_RS15075 in Parabacteroides merdae CL09T00C40

Annotation: type I-C CRISPR-associated protein Cas7/Csd2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 288 TIGR01595: CRISPR-associated protein, CT1132 family" amino acids 5 to 274 (270 residues), 294.8 bits, see alignment E=6.6e-92 PF05107: Cas_Cas7" amino acids 7 to 274 (268 residues), 358.8 bits, see alignment E=8.3e-112 TIGR02589: CRISPR-associated protein Cas7/Csd2, subtype I-C/DVULG" amino acids 8 to 286 (279 residues), 397.5 bits, see alignment E=3.5e-123

Best Hits

KEGG orthology group: None (inferred from 68% identity to dpr:Despr_1489)

Predicted SEED Role

"CRISPR-associated protein, Csd2/Csh2 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (288 amino acids)

>HMPREF1078_RS15075 type I-C CRISPR-associated protein Cas7/Csd2 (Parabacteroides merdae CL09T00C40)
METAINNRYDFIYLFDVQDGNPNGDPDAGNLPRVDPETGEGLVSDVCLKRKVRNFVQIVK
GGERLYDIFIKEKAVLNNLIADAHKQEGVKDIKEKGDKTEAARQWMCRNFYDIRTFGAVL
STGENAGQVRGPIQFTFARSISPIVTAEHSITRMAVATEDEAKKQSGDNRTMGRKFTVPY
GLYKANGFISAHLAAQTGFNEDDLNLFWDSLKNMFDHDHSAARGMMNARKLIVFKHSTAL
GNASAHSLFGLVKVQLKDDQRPPRSFDDYIVTIDKDKLPEGVEVLDMI