Protein Info for HMPREF1078_RS14915 in Parabacteroides merdae CL09T00C40

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 435 transmembrane" amino acids 18 to 41 (24 residues), see Phobius details amino acids 53 to 69 (17 residues), see Phobius details amino acids 81 to 107 (27 residues), see Phobius details amino acids 111 to 132 (22 residues), see Phobius details amino acids 150 to 170 (21 residues), see Phobius details amino acids 178 to 198 (21 residues), see Phobius details amino acids 237 to 255 (19 residues), see Phobius details amino acids 279 to 301 (23 residues), see Phobius details amino acids 309 to 329 (21 residues), see Phobius details amino acids 335 to 361 (27 residues), see Phobius details amino acids 371 to 391 (21 residues), see Phobius details amino acids 403 to 422 (20 residues), see Phobius details PF07690: MFS_1" amino acids 30 to 360 (331 residues), 44.9 bits, see alignment E=8e-16 PF03092: BT1" amino acids 31 to 240 (210 residues), 27.9 bits, see alignment E=1e-10

Best Hits

KEGG orthology group: K08218, MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG (inferred from 75% identity to bvu:BVU_2595)

Predicted SEED Role

"AmpG permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (435 amino acids)

>HMPREF1078_RS14915 MFS transporter (Parabacteroides merdae CL09T00C40)
MISYKPMSDKPSVRSPWFWVPSLYFAQGIPYVAVMIVSVLMYKRLGVSNTDIALYTSWLN
LPWVIKPFWSPFVDLLKTKRWWVATMQLLIGAGLAGVAFTIPTTFFFQASLAVFWLLAFS
SATHDIAADGFYMLALDSHEQAFFVGIRSTFYRIAIIAGQGVLVMFAGFLENSTGNIPLA
WSVTFFILGGLFLALFLYHRYILPLPKGDKPSATVTPSTILKEFFATFASFFKKKQAFVA
ILFMLLYRFPEAQLTKLVTPFLVDPREVGGLGLSTAEIGLVYGTIGTIGLTLGGILGGIA
ASAGGLKKWIWPMALAISLPDAVFIYLSSALPDNLWIVNICVFIEQFGYGFGFTAYMLYL
IYYSDGEHKTAHYAICTAFMALGLMLPGMAAGWLQEQMGYENFFWWVMGCCLVTLLVTAC
LKIDPEFGKKKQGNN